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  1. 20 Aug 2014
    Budesonide for maintenance of remission in Crohn's disease Updated
    Budesonide is a corticosteroid drug which is rapidly broken down by the liver, reducing corticosteroid-related side effects (e.g., moon face). Research showing that budesonide is effective in treating active Crohn's disease has led to clinical trials examining the effect of budesonide on reducing disease recurrence in non-active Crohn's disease. This ...
  2. 20 Aug 2014
    Motivational interviewing (MI) for alcohol misuse in young adults is not effective enough New
    Review question We reviewed the evidence about the effect of MI (a two-way approach of guiding others to bring out and strengthen the reasons for change) for alcohol misuse (risky, damaging or too much drinking) in young people. We found 66 studies. Background Damaging use of alcohol results in about 2.5 million deaths each year worldwide. About ...
  3. 20 Aug 2014
    Effectiveness of dental auxiliaries performing clinical tasks traditionally provided by a dentist New
    Background Some tasks undertaken by dentists could be delegated to appropriately trained dental auxiliaries, which might liberate time for dentists to undertake more complex procedures and could improve access to dental care and reduce costs. However, before such an approach can be advocated, it is important to know the relative effectiveness of dental ...
  4. 19 Aug 2014
    Interventions that aim to reduce body temperature to between 35 ºC and 37.5 ºC in patients who have had a traumatic brain injury within the last week Updated
    Traumatic brain injury (an injury to the brain that occurs as a result of a direct impact, such as may occur after a road traffic accident or a fall) is a major cause of death and long-term disability worldwide. There is some evidence from animal experiments that reducing body temperature after brain injury may improve outcomes. There is also some evidence ...
  5. 19 Aug 2014
    Reducing unwanted movement of teeth during treatment with orthodontic braces, comparing surgically placed implants as stabilisers (anchors) with other conventional methods Updated
    Review question This review, produced by the Cochrane Oral Health Group, seeks to assess the effects of using implants surgically placed in bone in the mouth in order to stabilise (anchor) teeth during treatment with orthodontic braces and compares implants with the use of conventional methods. It also assesses the effects of different surgical anchorage ...
  6. 15 Aug 2014
    Interventions to reduce haemorrhage during myomectomy for treating fibroids Updated
    Background Some women have non-cancerous growths of the uterus, called fibroids. In a third of cases the fibroids produce symptoms, such as vaginal bleeding, that warrant treatment. The surgical removal of the fibroids, called myomectomy, is one of the treatment options for fibroids. It can be accomplished by either laparotomy (through an incision ...
  7. 15 Aug 2014
    Colchicine for treating acute gout attacks Updated
    We reviewed the evidence about the benefits and harms of colchicine in acute gout up to April 2014 and identified two trials. One trial included 43 participants and compared high-dose colchicine (1 mg of colchicine followed by 0.5 mg every two hours until the attack resolved or participants had side effects (total dose unspecified)) to placebo. The ...
  8. 15 Aug 2014
    Magnesium sulphate for preventing preterm birth in threatened preterm labour Updated
    Even short-term postponement of birth when labour begins early (before 37 weeks) can help improve outcomes for babies, as the woman can take corticosteroid drugs to help develop the baby's lungs in a short time. Magnesium sulphate is one of the drugs that has been used to try to stop the uterus contracting in women who go into labour too soon. This ...
  9. 15 Aug 2014
    Treatment for gum disease (periodontitis) for the management of disease involving the heart and blood vessels in patients with chronic gum disease New
    Review question The main question addressed by this review produced by the Cochrane Oral Health Group was whether or not treatment for moderate to severe gum disease (periodontitis) also has an effect on the prevention or management of heart and blood vessel (cardiovascular) disease. Background Gum disease (periodontitis) is a common chronic or ...
  10. 14 Aug 2014
    Hypnosis for induction of labour New
    Labour induction is the artificial stimulation of uterine contractions in order to bring about birth. It is commonly used in late pregnancy to address maternal and fetal problems. Induction of labour using pharmacological and mechanical methods can cause complications or side-effects such as bleeding, caesarean section uterine hyperstimulation and maternal ...

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