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  1. 31 Aug 2014
    Minimally invasive versus surgical treatment of an aneurysm of the popliteal artery New
    The popliteal artery is a blood vessel situated behind the knee joint. Sometimes it weakens and expands like a balloon, known as an aneurysm. If left untreated, the blood clot within the aneurysm may embolise or the aneurysm may rupture or get blocked. Any of these complications can lead to limb loss or even death. Traditionally, popliteal artery aneurysm ...
  2. 31 Aug 2014
    Is the blood pressure lowering effect of dihydropyridine calcium channel blockers consistent or variable throughout 24 hours? New
    Background High blood pressure, also known as hypertension, is a risk factor for adverse cardiovascular events such as stroke and heart attack. Blood pressure varies widely in an individual but certain patterns in its rise and fall have been identified in the general population; blood pressure increases in the early morning hours and decreases during ...
  3. 30 Aug 2014
    Removal of endometrial polyps prior to infertility treatment New
    Review question Cochrane authors investigated whether the removal of endometrial polyps in women presenting with subfertility was safe and whether it improved the chance of pregnancy. Background Endometrial polyps, which are benign and often asymptomatic growths of the lining of the womb, have the potential to interfere with female fertility. This ...
  4. 29 Aug 2014
    Anti-vascular endothelial growth factor for neovascular age-related macular degeneration Podcast Updated
    Background Age-related macular degeneration (AMD) is a common cause of severe vision loss in people 55 years and older. Neovascular AMD, which involves abnormal growth of blood vessels in the back of the eye, accounts for most AMD-related severe vision loss. Injections into the eye of medications, such as pegaptanib, ranibizumab, and bevacizumab, that ...
  5. 29 Aug 2014
    Do exercise interventions help people quit smoking Podcast Updated
    Review question We reviewed the evidence about the effect of exercise programmes in people who want to quit smoking. We looked at whether exercise programmes, either alone or combined with stop smoking programmes, helped more people to quit at six months or longer than stop smoking programmes alone or stop smoking programmes combined with health education. Background Specialist ...
  6. 29 Aug 2014
    Prevention of blood clots in non-hospitalised cancer patients receiving chemotherapy Updated
    Cancer patients are more likely than patients without cancer to develop blood clots in their veins (venous thromboembolism or VTE). Chemotherapy further increases this risk. Yet bleeding at the site of the cancer and a relative decrease in the number of platelets in the blood (thrombocytopenia) that is caused by chemotherapy may make cancer patients ...
  7. 28 Aug 2014
    Systematic review of randomised controlled trials about the efficacy and safety of colchicine in people with pericarditis New
    Pericarditis is the inflammation and swelling of the tissue covering the outer layer of the heart. Pericarditis causes severe and disabling chest pain and fever, however the main issue is the repeated recurrence of pericarditis attacks. Colchicine is an ancient medication that has been used in the treatment of other inflammatory diseases such as gout. We ...
  8. 28 Aug 2014
    Treatments for acute bleeds in people with acquired hemophilia A New
    Acquired hemophilia A is a rare but severe bleeding disorder caused by the autoantibody directed against factor VIII (FVIII, a blood clotting protein) in patients with no previous history of a bleeding disorder. This bleeding disorder occurs more frequently in the elderly and may be associated with several other conditions, such as solid tumours, autoimmune ...
  9. 27 Aug 2014
    Haemodilution for acute ischaemic stroke Updated
    Question We wanted to compare the effectiveness of haemodilution (diluting the blood) treatment, started within 72 hours of stroke onset, versus control or no treatment in people with ischaemic stroke to assess the impact on death or dependence. Background Stroke is the second leading cause of death worldwide. Symptoms of stroke include face drooping, ...
  10. 27 Aug 2014
    Methotrexate for treatment of chronic active ulcerative colitis Updated
    Ulcerative colitis is a chronic inflammatory bowel disease characterized by abdominal cramping, fecal urgency and bloody diarrhea. Methotrexate is a drug that suppresses the body's natural immune responses and may suppress inflammation associated with ulcerative colitis. The purpose of this systematic review was to examine the effectiveness and side ...

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