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  1. 22 Nov 2014
    Aspiration of the elbow joint for treating radial head fractures New
    What is a radial head fracture? The radial head is the topmost part of the radius, which is one of the two forearm bones. The radial head is part of the elbow joint. Fracture or breaking of the radial head is the most common elbow fracture. This injury usually results from a fall onto an outstretched arm. The symptoms of a radial head fracture are ...
  2. 21 Nov 2014
    Amantadine and rimantadine to prevent and treat influenza A in children and the elderly Updated
    Review question As recommended by the World Health Organization (WHO), oseltamivir (Tamiflu) is currently used for people with influenza A. In previous pandemics, the virus was susceptible to amantadine and rimantadine. If they are safe and the circulating strain proves to be susceptible to these drugs, they could be an alternative for managing influenza. ...
  3. 21 Nov 2014
    Tranexamic acid, an agent that promotes blood clotting, for serious or uncontrolled upper gastrointestinal bleeding Updated
    Background Upper gastrointestinal bleeding is a common reason for emergency hospital admission. The prognosis is serious. Some patients may die as the result of uncontrolled bleeding. Review question Tranexamic acid is an antifibrinolytic agent. This drug reduces the breakdown of fibrin; fibrin provides the framework for the formation of a blood ...
  4. 21 Nov 2014
    The effect of rosuvastatin on cholesterol New
    Rosuvastatin (Crestor) is one of the most potent statins and is currently widely prescribed. It is therefore important to know how much rosuvastatin lowers cholesterol. We searched for all the trial evidence from trials of three to 12 week duration reporting the effect of rosuvastatin on cholesterol. We found 108 trials involving 19,596 participants. ...
  5. 20 Nov 2014
    Ways to help people follow prescribed medicines Podcast Updated
    Background Patients who are prescribed medicines take only about half of their doses and many stop treatment entirely. Assisting patients to adhere better to medicines could improve their health, and many studies have tested ways to achieve this. Question We updated our review from 2007 to answer the question: What are the findings of high-quality ...
  6. 20 Nov 2014
    Surgical interventions for chronic rhinosinusitis with nasal polyps New
    Background Benign nasal polyps are abnormal tissue growths inside the nasal passages and sinuses, often on both sides of the nose. They can cause a wide array of symptoms including blocked nose, poor sense of smell that can lead to a loss of taste, runny nose and nasal congestion. Sinuses are air-filled cavities in the bones of the face, which are ...
  7. 20 Nov 2014
    Home versus in-centre haemodialysis for end-stage kidney disease New
    Numerous studies observing people who are treated with haemodialysis at home show they have better quality of life and survival, but such analyses are not randomised (that is, participants treated with home haemodialysis may be younger and have fewer health problems that explain the improvements in outcomes observed). Home haemodialysis may also increase ...
  8. 20 Nov 2014
    Treating unintentional hypothermia after surgery New
    Review question We wanted to find out the effects of different methods of rewarming adult patients with unintentional hypothermia (a core body temperature below 36°C) after surgery. Background Patients can get cold during surgery, particularly because of the drugs used as anaesthetics. This can cause potentially dangerous heart problems. Cold can ...
  9. 20 Nov 2014
    Outpatient versus inpatient treatment for acute pulmonary embolism New
    Background Pulmonary embolism (PE) is a common life-threatening cardiovascular condition, with 23 to 69 new cases per 100,000 people per year. Outpatient treatment instead of traditional inpatient treatment in selected low-risk patients with acute (sudden-onset) PE might provide several advantages such as reduction of hospital admissions, substantial ...
  10. 19 Nov 2014
    Surgical removal of the tonsils (tonsillectomy) for chronic or recurrent acute tonsillitis Updated
    Review question This review compared the clinical effectiveness and safety of surgery (removal of the tonsils - tonsillectomy, or adenotonsillectomy - removal of the tonsils and adenoid tissues) against non-surgical management in adults and children with frequent or chronic tonsillitis. Background Surgical removal of the tonsils is a commonly performed ...

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