Cochrane Summariesbeta

Independent high-quality evidence for health care decision making
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  1. Additional bedtime medication for the control of night-time acid reflux from the stomach.
    The inhibition of gastric acid secretion is an accepted treatment for diseases related to reflux of acid from the stomach. Some types of antacids, known as proton pump inhibitors (PPI), are considered to be the most effective medical treatment for people patients with acid-related diseases such as peptic ulcer, gastro-oesophageal reflux disease (GERD) ...
  2. Use of antibiotics to prevent infection of dead pancreatic tissue in acute pancreatitis
    Acute pancreatitis is the inflammation of the pancreas, a serious emergency with no specific treatment. The pancreas, a digestive gland, can become inflamed for many reasons, but mainly as a complication from gallstones or excess alcohol intake. If severe, the pancreas may lose its blood supply, a complication called pancreatic necrosis that can be ...
  3. No strong evidence about the effectiveness of Argon Plasma Coagulation therapy over other interventions for gastrointestinal bleeding.
    Bleeding in the digestive tract can be controlled by the injection of chemicals into the site of the bleeding, or by laser therapy or heater probe. Argon plasma coagulation (APC) therapy uses argon gas and electrical current to stop the bleeding without contact. Very few trials are available and more are needed to determine whether APC is more effective ...
  4. Chemotherapy and radiotherapy may improve survival and quality of life in people with advanced pancreatic cancer
    Advanced pancreatic cancer is incurable. Symptoms affect quality of life, and life expectancy is reduced. This review investigated the effect of chemotherapy and radiotherapy on survival and symptoms, and found that having chemotherapy (compared to no chemotherapy) improved survival, and sometimes symptoms and quality of life. Chemotherapy using drug ...
  5. Chinese medicinal herbs for treating acute inflammation of the pancreas
    The pancreas is a gland near the stomach that helps digestion by secreting insulin into the blood and digestive enzymes into the small intestine. Acute pancreatitis is a relatively common acute abdominal emergency with no specific therapy. It is potentially fatal. In China, traditional Chinese medicinal herbs have been used for many years to treat acute ...
  6. Traditional Chinese medicinal herbs for induction of remission in advanced or late gastric cancer
    Gastric cancer, one of the malignant tumours with the highest morbidity in gastrointestinal tract, may easily lead to death once it progresses to an advanced or late stage. There are few interventions which can postpone or stop the malignant course of the illness. However, some kinds of traditional Chinese medicinal herbs (TCMHs), as an alternative ...
  7. Cisapride treatment for gastro-oesophageal reflux in young children
    Gastro-oesophageal reflux is the movement of stomach contents back into the oesophagus. A ring of smooth muscle (sphincter) at the lower end of the oesophagus near the stomach usually prevents this regurgitation. Relaxation of the sphincter, ineffective clearance of food from the oesophagus into the stomach, and delayed emptying of the stomach can all ...
  8. A combination of chemotherapy and radiotherapy is more effective than radiotherapy alone for localised cancer of the esophagus (gullet).
    Cancer of the esophagus (gullet) is a life threatening cancer with relatively few symptoms until it becomes advanced. People with esophageal cancer have a low survival rate. The cancer quickly spreads and does not always show symptoms at the original site of the disease. Surgery is one option, radiotherapy (using radiation) and chemotherapy (using drug) ...
  9. Patients with a predicted severe attack of callsone-associated acute pancreatitis need early endoscopic retrograde cholangiopancreatography
    Patients presenting with acute pancreatitis may benefit from treatment to reduce complications and mortality. Early endoscopic retrograde cholangio-pancreatography with or without sphincterotomy has been advocated for acute pancreatitis associated with gallstones since the late 1980s. A more recent multicentre trial, however has suggested that it may ...
  10. Nutritional support, through the intestine (enteral) versus by injection (parenteral) for people with acute pancreatitis
    The pancreas is a gland that lies behind the stomach. It produces enzymes that help digestion. Acute pancreatitis is an inflammation in the pancreas which causes severe pains in the stomach. Extra nutrition is needed to recover. However the pancreas needs rest in order to repair. Nutrition must therefore be given either by a tube into the intestines ...

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