Cochrane Summariesbeta

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  1. Acellular vaccines for preventing whooping cough in children
    Whooping cough (pertussis) can be a serious respiratory infection. Vaccines made from killed whole Bordetella pertussis (B. pertussis) were developed, but they could cause serious and permanent nervous system disorders such as convulsions, encephalopathy and hypotonic-hyporesponsive episodes, as well as minor adverse events, such as anorexia, drowsiness, ...
  2. Mucolytic drugs to treat acute upper and lower respiratory tract infections in children without chronic broncho-pulmonary disease
    Acetylcysteine and carbocysteine are the most commonly prescribed mucolytic drugs. This systematic review aimed at assessing their efficacy and safety for treating acute upper and lower respiratory tract infections (ARTIs) in children without chronic broncho-pulmonary disease. A subgroup analysis among patients younger than two years was performed. Forty-nine ...
  3. Acyclovir can reduce the number of days with fever in otherwise healthy children with chickenpox, but its effect on sores and itching is not yet certain
    Chickenpox (varicella) is caused by a virus. It begins with a fever, followed by a rash of red pimples which become itchy sores that form scabs. Chickenpox usually affects children from one to 14 years. In young babies, adults or people with impaired immune system, chickenpox is more severe. Treatments include lotions to relieve itchiness, paracetamol ...
  4. Advising patients to increase fluid intake for treating acute respiratory infections
    Doctors commonly recommend that people with acute respiratory infections drink extra fluids. Acute infections include colds, acute sinusitis, tonsillitis, laryngitis, bronchitis, pneumonia and influenza. This review intended to find out the benefit or harm from this recommendation. Potential benefits of fluids are replacing fluid lost because of fever ...
  5. Antiviral drugs amantadine and rimantadine for preventing and treating the symptoms of influenza A in adults
    The drugs amantadine and rimantadine can both help prevent and relieve the symptoms of influenza A in adults, but amantadine has more adverse effects. The flu can be caused by many different viruses. One type is influenza A, with headaches, coughs and runny noses that can last for many days and lead to serious illnesses such as pneumonia. Amantadine ...
  6. Amantadine and rimantadine to prevent and treat influenza A in children and the elderly Updated
    Influenza is a respiratory infection in which cough, runny nose, headache and fever are frequent manifestations. Most symptoms resolve without treatment within three to seven days. However, hospitalisation, pneumonia and even death may occur as rare complications of the illness, especially among children and the elderly. Pandemics are also a reason ...
  7. Antibiotics to help reduce mortality and respiratory infections in people receiving intensive care in hospital
    Infections acquired in intensive care units (ICUs) are important complications of the treatment of patients with very severe diseases who need ventilation (mechanical breathing support). Some people will die because of these infections. Considerable efforts have been made to evaluate methods for reducing this problem; one of these involves the use of ...
  8. Antibiotics for adults with acute laryngitis
    Acute laryngitis is an inflammation of the larynx. The most common symptoms are hoarseness, fever, sore throat, postnasal discharge and difficulty in swallowing. Antibiotics are frequently prescribed by physicians or self-prescribed. Reasons for over-prescribing antibiotics in upper respiratory tract infection such as acute laryngitis are varied but ...
  9. Antibiotics for acute maxillary sinusitis
    Sinusitis is one of the most common reasons for visiting a doctor, with 20 million visits for this condition every year in the USA alone. There are four pairs of sinuses linked to the bony structures around the nose: the maxillary, frontal, ethmoidal and sphenoidal sinuses. In sinusitis, these membrane-lined air spaces become infected, which causes ...
  10. Antibiotics for reducing the pain of middle ear infection (acute otitis media) in children
    Acute otitis media (AOM) is common in children, causing pain and deafness. Though AOM usually resolves without treatment, it is often treated with antibiotics. This review found that antibiotics are not very useful for most children with AOM. Antibiotics marginally decreased the number of children with pain at 24 hours (when most children were better), ...

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