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  1. 20 Aug 2014
    Motivational interviewing (MI) for alcohol misuse in young adults is not effective enough New
    Review question We reviewed the evidence about the effect of MI (a two-way approach of guiding others to bring out and strengthen the reasons for change) for alcohol misuse (risky, damaging or too much drinking) in young people. We found 66 studies. Background Damaging use of alcohol results in about 2.5 million deaths each year worldwide. ...
  2. 24 Jun 2014
    Maintenance treatments for opiate-dependent adolescents
    Review question We reviewed the evidence about the effect of maintenance treatment either alone or associated with psychosocial intervention compared with no intervention, placebo, other pharmacological intervention, pharmacological detoxification or psychosocial intervention in adolescents (13 to 18 years). Background Substance abuse among adolescents ...
  3. 3 Jun 2014
    Do printed self-help materials containing information about how to give up smoking help people to quit
    Background We reviewed the evidence that printed materials giving structured advice about how to stop smoking help people to quit. We looked for trials of any type of printed self-help material which gave structured support and advice about quitting. We also included materials in audio or video format but we did not include internet programmes or ...
  4. 29 Apr 2014
    Detoxification treatments for opiate dependent adolescents
    Detoxification treatment for heroin dependents adolescents Review question We reviewed the evidence on the effect of detoxification treatment compared with pharmacological maintenance treatment or psychosocial intervention in achieving abstinence on adolescents heroin dependents. Background Substance abuse among adolescents (13 to 18 years old) ...
  5. 31 Mar 2014
    Clonidine, lofexidine and similar medications for the management of opioid withdrawal
    Review question We reviewed the evidence about the effect of alpha2-adrenergic agonists (clonidine, lofexidine, guanfacine and tizanidine) in managing withdrawal in people who are dependent on opioid drugs (eg , heroin, methadone). Background Managed withdrawal, or detoxification, is a required first step for longer-term treatments of opioid dependence. ...
  6. 27 Mar 2014
    Can people be helped to stop smoking before they have surgery?
    Smoking is a well-known risk factor for complications after surgery. Stopping smoking before surgery is likely to reduce the risk of complications. We reviewed the evidence about the effects of providing smoking cessation interventions to people awaiting surgery on their success in quitting at the time of surgery and longer-term, and at complications ...
  7. 1 Mar 2014
    Can interventions for parents and people caring for children reduce children's exposure to tobacco smoke
    Background Children exposed to cigarette smoke (environmental tobacco smoke) are at greater risk of lung problems, infections and serious complications including sudden infant death syndrome. Preventing exposure to cigarette smoke in infancy and childhood might therefore significantly improve children's health worldwide. Parental smoking is a common ...
  8. 26 Feb 2014
    Is the workplace an effective setting for helping people to stop smoking Podcast
    Background The workplace appears to be a useful setting for helping people to stop smoking. Large groups of smokers are available who can easily be reached and helped, using proven methods. It is also in the employers’ interests to improve the health of their workforce. Recent changes introducing anti-smoking laws in many developed countries may have ...
  9. 13 Feb 2014
    Anticonvulsants for alcohol dependence
    Review question This review looked at evidence on the efficacy and acceptability of anticonvulsants alone or in combination with another medication or a psychosocial intervention for the treatment of alcohol dependence. Background Alcohol dependence is a major public health problem characterised by recidivism and a host of medical and psychosocial ...
  10. 6 Feb 2014
    Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence
    Background Methadone is widely used as a replacement for illicit opioid use such as heroin in medically-supported opioid substitution maintenance programmes. Two other drugs have been used to help reduce illicit opioid use, specifically buprenorphine and LAAM (levo-alpha-acetylmethadol). LAAM is not used in current clinical practice. Buprenorphine ...

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