Cochrane Summaries

Independent high-quality evidence for health care decision making

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  1. Apr 2013
    A review of unpublished regulatory information from trials of neuraminidase inhibitors (Tamiflu - oseltamivir and Relenza - zanamivir) for influenza Podcast
    We decided to update and amalgamate our reviews on the antiviral drugs zanamivir and oseltamivir for influenza on the basis of the manufacturers' reports to regulators (called clinical study reports) and regulators' comments (which we called regulatory information). Clinical study reports are extensive documents with exhaustive details of the trial ...
  2. Mar 2013
    Chinese medicinal herbs for influenza
    Influenza is a viral respiratory infection that causes an acute febrile illness with myalgia, headache and cough, and can result in high morbidity and mortality rates during an epidemic. Annual epidemics are thought to result in between three and five million cases of severe influenza and between 250,000 and 500,000 deaths worldwide. Currently, annual ...
  3. Feb 2013
    Homeopathic Oscillococcinum® for preventing and treating influenza and influenza-like illness
    Influenza ('the flu') is a highly infectious viral respiratory disease. Other than treatments for complications (such as pneumonia), the conventional medical strategies for the prevention or treatment of flu are not entirely effective or satisfactory. Oscillococcinum® is a highly diluted homeopathic preparation manufactured from wild duck heart and ...
  4. Aug 2012
    Vaccines for preventing influenza in healthy children
    Children (< 16 years old) and the elderly (above 65 years old) are the two age groups that appear to have the most complications following an influenza infection. Influenza has a viral origin and often results in an acute respiratory illness affecting the lower or upper parts of the respiratory tract, or both. Viruses are mainly of two subtypes (A ...
  5. Jul 2012
    Antiviral drugs amantadine and rimantadine for preventing and treating the symptoms of influenza A in adults
    The drugs amantadine and rimantadine can both help prevent and relieve the symptoms of influenza A in adults, but amantadine has more adverse effects. The flu can be caused by many different viruses. One type is influenza A, with headaches, coughs and runny noses that can last for many days and lead to serious illnesses such as pneumonia. Amantadine ...
  6. Apr 2012
    Combined DTP-HBV-HIB vaccine versus separately administered DTP-HBV and HIB vaccines in healthy infants up to two years old Podcast
    Childhood vaccinations provide an effective method of protection against diseases. The World Health Organization (WHO) recommends that routine infant immunisation programmes include a vaccination against Haemophilus influenzae (H. influenza) type B (HIB) in the combined diphtheria-tetanus-pertussis (DTP)-hepatitis B virus (HBV) vaccination. We compared ...
  7. Apr 2012
    Neuraminidase inhibitors for preventing and treating influenza in children
    Influenza (true 'flu) is an infection of the airways caused by the Influenza group of viruses. Influenza occurs most commonly during winter months and can result in symptoms such as fever, cough, sore throat, headache, muscle aches and fatigue. These are usually self limiting but may persist for one to two weeks. The most common complications of influenza ...
  8. Jan 2012
    Amantadine and rimantadine to prevent and treat influenza A in children and the elderly
    Influenza is a respiratory infection in which cough, runny nose, headache and fever are frequent manifestations. Most symptoms resolve without treatment within three to seven days. However, hospitalisation, pneumonia and even death may occur as rare complications of the illness, especially among children and the elderly. Pandemics are also a reason ...
  9. Dec 2011
    Antiviral treatment for influenza infection in people with cystic fibrosis
    Cystic fibrosis is a genetic, life-threatening disorder affecting multiple organs. People with cystic fibrosis have a higher risk of chronic lung disease. Influenza can worsen the course of the disease in cystic fibrosis by increasing the risk of pneumonia and secondary respiratory complications. During a pandemic, flu symptoms may be more severe and ...
  10. Aug 2011
    Vaccines for preventing influenza in people with cystic fibrosis
    People with cystic fibrosis have blocked airways which results in frequent airway infections. Infections with viral diseases like influenza ("the flu") can worsen lung damage. Doctors therefore often advise people with cystic fibrosis to be vaccinated against influenza every year. We searched for studies which compared different vaccines or compared ...

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