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  1. 21 Nov 2014
    Amantadine and rimantadine to prevent and treat influenza A in children and the elderly Updated
    Review question As recommended by the World Health Organization (WHO), oseltamivir (Tamiflu) is currently used for people with influenza A. In previous pandemics, the virus was susceptible to amantadine and rimantadine. If they are safe and the circulating strain proves to be susceptible to these drugs, they could be an alternative for managing influenza. ...
  2. 7 Jul 2014
    Interventions to increase influenza (flu) vaccination uptake for people aged 60 and older
    Many health authorities recommend influenza vaccination of older people. However, vaccination uptake in people aged 60 and older varies across countries, socioeconomic and health-risk groups. It is important to identify effective interventions to increase influenza vaccination uptake. We included 57 randomised controlled trials (RCTs) with 896,531 participants ...
  3. 10 Apr 2014
    Regulatory information on trials of oseltamivir (Tamiflu) and zanamivir (Relenza) for influenza in adults and children
    Oseltamivir and zanamivir have been stockpiled in many countries to treat and prevent seasonal and pandemic influenza, before an influenza vaccine matched to the circulating virus becomes available. Oseltamivir is classified by the World Health Organization as an essential medicine. How this review has been approached We have updated and combined ...
  4. 13 Mar 2014
    Vaccines to prevent influenza in healthy adults
    Review question We evaluated the effect of immunisation with influenza vaccines on preventing influenza A or B infections (efficacy), influenza-like illness (ILI) and its consequences (effectiveness), and determined whether exposure to influenza vaccines is associated with serious or severe harms. The target populations were healthy adults, including ...
  5. 6 Mar 2014
    Vaccines for preventing influenza in people with cystic fibrosis
    People with cystic fibrosis have blocked airways which results in frequent airway infections. Infections with viral diseases like influenza ("the flu") can worsen lung damage. Doctors therefore often advise people with cystic fibrosis to be vaccinated against influenza every year. We searched for studies which compared different vaccines or compared ...
  6. 10 Feb 2014
    Antiviral treatment for influenza infection in people with cystic fibrosis
    Cystic fibrosis is a genetic, life-threatening disorder affecting multiple organs. People with cystic fibrosis have a higher risk of chronic lung disease. Influenza can worsen the course of the disease in cystic fibrosis by increasing the risk of pneumonia and secondary respiratory complications. During a pandemic, flu symptoms may be more severe and ...
  7. 29 Oct 2013
    Influenza (flu) vaccination for preventing influenza in adults with cancer
    Adults with cancer are prone to serious complications from influenza, more than healthy adults. The influenza vaccine protects against influenza and its complications. However, its effectiveness among cancer patients is unclear, as the immune dysfunction that accompanies cancer and as a result of chemotherapy might lower immune response to the vaccine. ...
  8. 1 Aug 2013
    Influenza vaccination in children being treated with chemotherapy for cancer
    Children with cancer are prone to developing infections. One of the viral infections is influenza (flu). This can run an innocent course in these children but some can develop severe complications. This review therefore focused on the efficacy of influenza vaccination in children with cancer. We identified no studies which assessed the clinical efficacy ...
  9. 23 Jul 2013
    Influenza vaccination for healthcare workers who care for people aged 60 or older living in long-term care institutions
    Older individuals in long-term care institutions (LTCIs) at risk of influenza may be infected by their healthcare workers. There are no accurate data on rates of laboratory-proven influenza in healthcare workers. Vaccinating healthcare workers against influenza may reduce infections acquired from this source. Because the signs and symptoms of influenza ...
  10. 31 May 2013
    Homeopathic Oscillococcinum® for preventing and treating influenza and influenza-like illness
    Influenza ('the flu') is a highly infectious viral respiratory disease. Other than treatments for complications (such as pneumonia), the conventional medical strategies for the prevention or treatment of flu are not entirely effective or satisfactory. Oscillococcinum® is a highly diluted homeopathic preparation manufactured from wild duck heart and ...

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