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  1. 10 Apr 2014
    Regulatory information on trials of oseltamivir (Tamiflu) and zanamivir (Relenza) for influenza in adults and children Podcast Updated
    Oseltamivir and zanamivir have been stockpiled in many countries to treat and prevent seasonal and pandemic influenza, before an influenza vaccine matched to the circulating virus becomes available. Oseltamivir is classified by the World Health Organization as an essential medicine. How this review has been approached We have updated and combined ...
  2. 9 Apr 2014
    Drugs to control the movement of salt in the lungs of people with cystic fibrosis Updated
    Usually salt is absorbed from liquid on the surface of the lungs to stop fluid building up there. In cystic fibrosis too much salt is absorbed and there is little liquid left on the airway surfaces. As a result people with cystic fibrosis have problems clearing their lungs of sticky secretions. Thus the lungs are left open to infection. Drugs applied ...
  3. 2 Apr 2014
    Antibiotic treatment for Stenotrophomonas maltophilia in people with cystic fibrosis Updated
    Stenotrophomonas maltophilia is a bacteria which is resistant to several antibiotics. Over the last 10 years this bacteria has increasingly been found in the lungs of people with cystic fibrosis. Chronic infection with Stenotrophomonas maltophilia has been found to be linked to pulmonary infections. However, at present, it is unclear if people with ...
  4. 1 Apr 2014
    Antibodies for preventing measles after exposure New
    People who have had measles, or measles vaccine, have antibodies against the virus in their blood that protect them from developing measles should they come into contact with it. These antibodies can be extracted from blood donated by these individuals. If people without antibodies come into contact with someone who is contagious with measles, they ...
  5. 27 Mar 2014
    Can people be helped to stop smoking before they have surgery? Updated
    Smoking is a well-known risk factor for complications after surgery. Stopping smoking before surgery is likely to reduce the risk of complications. We reviewed the evidence about the effects of providing smoking cessation interventions to people awaiting surgery on their success in quitting at the time of surgery and longer-term, and at complications ...
  6. 26 Mar 2014
    Which long-acting inhaled drugs, used alone or in combination, are the most effective for people with COPD? New
    Why is this question important? Inhaled drugs for COPD have been shown to relieve symptoms, improve quality of life and prevent or treat flare-ups. Treatment with these inhaled drugs tends to begin with one inhaler, and additional therapies are introduced as necessary. For persistent or worsening symptoms, long-acting inhaled drugs taken once or ...
  7. 25 Mar 2014
    Steroidal anti-inflammatory medication given by mouth or injection for acute sinusitis Updated
    Review question We reviewed the evidence about the effect of steroidal anti-inflammatory medication (i.e. corticosteroids) given by mouth or injection (i.e. systemically) compared to placebo or standard clinical care on acute attacks of nose and sinus complaints (i.e. acute sinusitis) in children and adults. Background Acute sinusitis may be caused ...
  8. 24 Mar 2014
    Self management for patients with chronic obstructive pulmonary disease Updated
    Background Symptoms of patients with COPD slowly worsen over the years. This leads to loss of well-being in these patients. In research, another word for well-being is health-related quality of life. Self management training teaches patients the skills and behaviours they need to successfully manage their disease. Self-management training is becoming ...
  9. 13 Mar 2014
    Vaccines to prevent influenza in healthy adults Podcast Updated
    Review question We evaluated the effect of immunisation with influenza vaccines on preventing influenza A or B infections (efficacy), influenza-like illness (ILI) and its consequences (effectiveness), and determined whether exposure to influenza vaccines is associated with serious or severe harms. The target populations were healthy adults, including ...
  10. 11 Mar 2014
    Over-the-counter medications to help reduce cough for children and adults on antibiotics for acute pneumonia Updated
    There are many causes of acute cough, one of which is pneumonia. Cough is burdensome and impairs quality of life. Over-the-counter (OTC) medications are commonly purchased and used by patients, and are recommended by healthcare staff as additional medications in the treatment of pneumonia. There are many classes of OTC medications for cough, such as ...

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