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  1. 21 Nov 2014
    Amantadine and rimantadine to prevent and treat influenza A in children and the elderly Updated
    Review question As recommended by the World Health Organization (WHO), oseltamivir (Tamiflu) is currently used for people with influenza A. In previous pandemics, the virus was susceptible to amantadine and rimantadine. If they are safe and the circulating strain proves to be susceptible to these drugs, they could be an alternative for managing influenza. ...
  2. 18 Nov 2014
    Reminder systems to improve patient attendance at tuberculosis clinics Updated
    This Cochrane Review summarizes trials evaluating the effects of reminder systems on attendance at tuberculosis (TB) clinics and completion of TB treatment. After searching for relevant trials up to 29 August 2014, we included nine trials, including 4654 people. What are reminder systems and how might they help? Effective treatment for TB requires ...
  3. 17 Nov 2014
    Cetuximab: a new treatment for advanced non-small cell lung cancer New
    Lung cancer is the most common cancer in the world. Advanced non-small cell lung cancer (NSCLC) accounts for about 60% of all lung cancer cases. Since the effectiveness of current standard treatment for advanced NSCLC (i.e. chemotherapy) has reached a ceiling, there is a continuous need for new, more effective treatments to further improve the outcome ...
  4. 13 Nov 2014
    PET-CT scanning to assess the spread of non-small cell lung cancer within the chest New
    In the absence of distant metastasis, treatment options for non-small cell lung cancer depend on how much the disease has spread to the different lymph nodes within the chest, that is, the stage of the disease. If the cancer has not spread beyond the nearest (N1) lymph nodes, surgery is often the treatment of choice. Other treatment options for these ...
  5. 12 Nov 2014
    Adjunctive steroid therapy for managing pulmonary tuberculosis New
    Pulmonary tuberculosis is a common infectious disease. Although curable with standard anti-pulmonary tuberculosis drugs, it has been reported that an individuals recovery could be improved by adding corticosteroids to their treatment. Current clinical guidelines advise the use of corticosteroids for treatment of other types of tuberculosis; tuberculosis ...
  6. 11 Nov 2014
    Garlic for the common cold Podcast Updated
    Background Garlic is popularly believed to be useful for the common cold. This belief is based on traditional use and some laboratory evidence that garlic has antibacterial and antiviral properties. On average, adults have two to four common colds per year. Study characteristics The evidence is current to the 7 August 2014. Of the eight studies ...
  7. 10 Nov 2014
    Different ways of giving antibiotics to eradicate Pseudomonas aeruginosa infection in people with cystic fibrosis Updated
    Review question We reviewed the evidence for the effectiveness of antibiotics in getting rid of a lung infection with a germ called Pseudomonas aeruginosa in people with cystic fibrosis. Background Cystic fibrosis is an inherited condition where the airways often become blocked with mucus. It is associated with chest infections, which can lead to ...
  8. 6 Nov 2014
    The usefulness of weaning protocols for reducing the time critically ill adult patients spend on mechanical ventilation Updated
    Review question: We reviewed the evidence about the effect of weaning protocols (guidelines) used by clinicians on reducing the time that critically ill patients spent on a breathing machine. Background: Helping patients to breathe with the use of a mechanical ventilator can be life saving. Yet the longer someone stays on a ventilator, the greater the ...
  9. 6 Nov 2014
    Use of rapid point-of-care testing for infection to guide doctors prescribing antibiotics for acute respiratory infections in primary care settings New
    Review question We reviewed the evidence of the effect and safety of a rapid test of infection at point-of-care for using antibiotics in people with acute respiratory infections (ARIs) (e.g. common colds) in primary care. Background Antibiotic treatment is common in ARIs despite the fact that the vast majority are caused by viruses, against which ...
  10. 3 Nov 2014
    Use of oral supplements to increase calorie intake in people with cystic fibrosis Updated
    We reviewed the evidence for the use of oral supplements to increase calorie intake in people with cystic fibrosis. Background Cystic fibrosis affects many organs, including the digestive system, and can lead to food not being absorbed as it should be, which in turn leads to growth problems. Children with cystic fibrosis need more energy than ...

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