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  1. 24 Nov 2014
    Over-the-counter (OTC) medications for acute cough in children and adults in community settings Updated
    Review question We undertook a review to determine the effectiveness of over-the-counter cough medicines in reducing cough in children and adults in community settings. We found 29 trials involving 4835 people. Background Acute cough is a common and troublesome symptom in children and adults suffering from acute upper respiratory tract infection ...
  2. 21 Nov 2014
    Amantadine and rimantadine to prevent and treat influenza A in children and the elderly Updated
    Review question As recommended by the World Health Organization (WHO), oseltamivir (Tamiflu) is currently used for people with influenza A. In previous pandemics, the virus was susceptible to amantadine and rimantadine. If they are safe and the circulating strain proves to be susceptible to these drugs, they could be an alternative for managing influenza. ...
  3. 19 Nov 2014
    Interventions aimed at communities for informing and/or educating about early childhood vaccination New
    Researchers in The Cochrane Collaboration conducted a review of the effect of informing or educating members of the community about early childhood vaccination. After searching for all relevant studies, they found two studies, published in 2007 and 2009. Their findings are summarised below. What are interventions aimed at communities for childhood ...
  4. 11 Nov 2014
    Garlic for the common cold Updated
    Background Garlic is popularly believed to be useful for the common cold. This belief is based on traditional use and some laboratory evidence that garlic has antibacterial and antiviral properties. On average, adults have two to four common colds per year. Study characteristics The evidence is current to the 7 August 2014. Of the eight studies ...
  5. 6 Nov 2014
    Use of rapid point-of-care testing for infection to guide doctors prescribing antibiotics for acute respiratory infections in primary care settings New
    Review question We reviewed the evidence of the effect and safety of a rapid test of infection at point-of-care for using antibiotics in people with acute respiratory infections (ARIs) (e.g. common colds) in primary care. Background Antibiotic treatment is common in ARIs despite the fact that the vast majority are caused by viruses, against which ...
  6. 29 Oct 2014
    Quantitative versus qualitative cultures of respiratory secretions in patients with ventilator-associated pneumonia Updated
    Review question We wanted to determine whether quantitative cultures of respiratory secretions are effective in reducing mortality in immunocompetent patients with ventilator-associated pneumonia compared with qualitative cultures. We also evaluated changes in antibiotic use, length of intensive care unit (ICU) stay and mechanical ventilation. Background Ventilator-associated ...
  7. 27 Oct 2014
    Decongestants, antihistamines and nasal irrigation for acute sinusitis in children Updated
    Review question The goal of this review was to determine whether there is any evidence in the medical literature for or against the use of decongestants, antihistamines and nasal irrigation for acute sinusitis in children. Background Young children experience an average of six to eight colds per year. Out of every 10 children with a cold, one develops ...
  8. 25 Oct 2014
    Probiotics for preventing ventilator-associated pneumonia New
    Review question To critically assess the current evidence from published studies relating to the effect of probiotics for preventing ventilator-associated pneumonia (VAP). Background VAP is a condition that can occur in patients who have been mechanically ventilated for more than 48 hours and can significantly increase the likelihood of death within ...
  9. 24 Oct 2014
    Treatments to cure long-term infections with Burkholderia cepacia in people with cystic fibrosis New
    Review question We reviewed the evidence for antibiotic treatment to cure early infection with Burkholderia cepacia complex in people with cystic fibrosis and prevent it becoming permanent. Background Cystic fibrosis is an inherited disease and people who have this disease produce large amounts of thick mucus which is difficult to clear. This mucus ...
  10. 9 Oct 2014
    Antibiotics for bronchiolitis in children under two years of age Updated
    Question We reviewed the evidence on the effect of antibiotics on clinical outcomes in children with bronchiolitis. Background Bronchiolitis is a serious respiratory illness that affects babies. It is most commonly caused by respiratory syncytial virus (RSV) and is the most common reason for hospitalisation in babies younger than six months. Babies ...

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