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  1. 10 Dec 2014
    Oxygen therapy as part of the treatment for respiratory infections in children Updated
    Review question We reviewed the evidence about the beneficial effect of oxygen supplementation therapy as part of the treatment for children with acute lower respiratory tract infection (LRTI). As oxygen may be administered using different delivery methods, we reviewed the most commonly used methods to deliver oxygen in children. As a secondary question, ...
  2. 3 Dec 2014
    Antibiotic treatment for nontuberculous mycobacteria in people with cystic fibrosis  Updated
    Nontuberculous mycobacteria are bacteria that are in the same family as tuberculosis and are commonly found in the soil and water. These bacteria can be found in the lungs of people with cystic fibrosis and can cause their lung function to worsen. Although there are guidelines on which antibiotics to use to treat lung infection due to these bacteria, ...
  3. 28 Nov 2014
    Treatments to fight fungal infections which cause allergic bronchopulmonary aspergillosis in people with cystic fibrosis Updated
    Review question We planned to review evidence about the effect of treatments to fight fungal infections which cause allergic bronchopulmonary aspergillosis in people with cystic fibrosis. Background Allergic bronchopulmonary aspergillosis (ABPA) is an allergic lung reaction to a type of fungus (usually Aspergillus fumigatus) in some people with ...
  4. 24 Nov 2014
    Over-the-counter (OTC) medications for acute cough in children and adults in community settings Updated
    Review question We undertook a review to determine the effectiveness of over-the-counter cough medicines in reducing cough in children and adults in community settings. We found 29 trials involving 4835 people. Background Acute cough is a common and troublesome symptom in children and adults suffering from acute upper respiratory tract infection ...
  5. 21 Nov 2014
    Amantadine and rimantadine to prevent and treat influenza A in children and the elderly Updated
    Review question As recommended by the World Health Organization (WHO), oseltamivir (Tamiflu) is currently used for people with influenza A. In previous pandemics, the virus was susceptible to amantadine and rimantadine. If they are safe and the circulating strain proves to be susceptible to these drugs, they could be an alternative for managing influenza. ...
  6. 19 Nov 2014
    Interventions aimed at communities for informing and/or educating about early childhood vaccination New
    Researchers in The Cochrane Collaboration conducted a review of the effect of informing or educating members of the community about early childhood vaccination. After searching for all relevant studies, they found two studies, published in 2007 and 2009. Their findings are summarised below. What are interventions aimed at communities for childhood ...
  7. 11 Nov 2014
    Garlic for the common cold Updated
    Background Garlic is popularly believed to be useful for the common cold. This belief is based on traditional use and some laboratory evidence that garlic has antibacterial and antiviral properties. On average, adults have two to four common colds per year. Study characteristics The evidence is current to the 7 August 2014. Of the eight studies ...
  8. 6 Nov 2014
    Use of rapid point-of-care testing for infection to guide doctors prescribing antibiotics for acute respiratory infections in primary care settings New
    Review question We reviewed the evidence of the effect and safety of a rapid test of infection at point-of-care for using antibiotics in people with acute respiratory infections (ARIs) (e.g. common colds) in primary care. Background Antibiotic treatment is common in ARIs despite the fact that the vast majority are caused by viruses, against which ...
  9. 29 Oct 2014
    Quantitative versus qualitative cultures of respiratory secretions in patients with ventilator-associated pneumonia
    Review question We wanted to determine whether quantitative cultures of respiratory secretions are effective in reducing mortality in immunocompetent patients with ventilator-associated pneumonia compared with qualitative cultures. We also evaluated changes in antibiotic use, length of intensive care unit (ICU) stay and mechanical ventilation. Background Ventilator-associated ...
  10. 27 Oct 2014
    Decongestants, antihistamines and nasal irrigation for acute sinusitis in children
    Review question The goal of this review was to determine whether there is any evidence in the medical literature for or against the use of decongestants, antihistamines and nasal irrigation for acute sinusitis in children. Background Young children experience an average of six to eight colds per year. Out of every 10 children with a cold, one develops ...

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