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  1. 28 Jan 2015
    Homeopathic Oscillococcinum® for preventing and treating influenza and influenza-like illness Updated
    Review question To determine whether homeopathic Oscillococcinum® is more effective than placebo in the prevention and/or treatment of influenza and influenza-like illness in adults or children. Background Influenza ('the flu') is a highly infectious viral respiratory disease. Other than treatments for complications (such as pneumonia), the conventional ...
  2. 28 Jan 2015
    Low dose versus high dose stavudine for treating people with HIV infection New
    Stavudine has been the most widely used antiretroviral agent as part of the combination therapy for treating HIV-1 infection in low-income countries. The use of stavudine has been associated with complications of redistribution of fat in the body, abnormalities in insulin and lipids, lactic acidosis and nerve problems. Some of these complications may ...
  3. 27 Jan 2015
    Screening with urinary dipsticks for reducing morbidity and mortality New
    Urinary dipsticks are sometimes used for screening healthy people and patients that do not have symptoms of urinary disease. Urinary dipsticks can be used to test for several different substances, such as blood, sugar, protein, white blood cells and nitrite in the urine, which may indicate the presence of disease. Identified abnormalities sometimes ...
  4. 26 Jan 2015
    Antibiotic prophylaxis during the second second and third trimester in pregnancy to reduce adverse pregnancy outcomes and morbidity Updated
    Antibiotics are administered to pregnant women during the second and third trimester of pregnancy (before labour) to prevent bacteria in the vagina and cervix affecting the pregnancy. Infection by some infectious organisms in a woman’s genital tract can cause health problems for the mother and her baby, and has been associated with preterm births. This ...
  5. 25 Jan 2015
    Macrolides for diffuse panbronchiolitis Updated
    Research question To summarise the evidence about the effect and safety of macrolide antibiotics for diffuse panbronchiolitis (DPB). Background DPB, characterised by progressive airflow limitation and recurrent respiratory tract infection (RTI), is a chronic airways disease that mainly affects people in east Asia. The prevalence of DPB in Japan ...
  6. 23 Jan 2015
    Pneumococcal vaccination during pregnancy for preventing infant infection Updated
    There is not enough evidence to assess whether using pneumococcal vaccination during pregnancy can prevent infant infections. Although the incidence of invasive pneumococcal disease is variable across the world, the rate of serious illness or death is high in children who get this infection. The Streptococcus pneumoniae (pneumococcus) organism colonizes ...
  7. 20 Jan 2015
    Procalcitonin, C-reactive protein, and erythrocyte sedimentation rate for the diagnosis of acute pyelonephritis in children New
    In some children with urinary tract infection (UTI), the infection is localized to the bladder (lower urinary tract). In others, bacteria ascend from the bladder to the kidney (upper urinary tract). Only children with upper urinary tract involvement are at risk for developing permanent kidney damage. If non-invasive biomarkers could accurately differentiate ...
  8. 15 Jan 2015
    Using oxygen at high pressure (in a compression chamber) for the treatment of individuals with severe soft tissue infection (necrotizing fasciitis) New
    Severe soft tissue infection (necrotizing fasciitis) is life threatening, is associated with prolonged hospital stay and carries high risk of long-term loss of function. Routine treatment consists of immediate surgical removal of infected tissue and administration of antibiotics. Use of hyperbaric oxygen therapy, or HBOT, in addition to surgery and ...
  9. 13 Jan 2015
    Antimalarial drugs as a treatment of anaemia in children living in malaria-endemic areas. New
    Children living in malaria areas may develop severe anaemia, often caused by malaria infection, and this can cause death if not treated properly. Intermittent preventive treatment (IPT) is a course of malaria treatment given regularly to these children in order to prevent infection and malaria illness. It has been suggested that IPT could be used to ...
  10. 9 Jan 2015
    Antiviral medicines, interferon, and corneal surface removal in the treatment of herpes simplex virus infection of the eye Updated
    Review question We compared different treatments of people's eyes infected with herpes simplex virus (HSV). Background HSV infection of the eye causes pain and hazy vision. Antiviral eye medicines, interferon drops, and superficial wiping have been used to cure HSV infection of the corneal surface. Study characteristics This update, current to December ...

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