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  1. 17 Sep 2014
    Acellular vaccines for preventing whooping cough (pertussis) in children Updated
    Review question We aimed to answer the question of whether acellular pertussis vaccines are as effective as the whole-cell vaccines at protecting children against whooping cough (pertussis), but with fewer side effects. Background Whooping cough can be a serious respiratory infection in children and is caused by the bacterium Bordetella pertussis ...
  2. 15 Sep 2014
    Rapid viral testing for children in the Emergency Department with fever and respiratory symptoms Updated
    Review question Does rapid viral testing in the Emergency Department influence the treatment of children with fever and breathing symptoms? Background Otherwise healthy children, aged 0 to 18 years, admitted to Emergency Departments (EDs) with fever and respiratory symptoms represent a major burden to the healthcare system, as well as significant ...
  3. 14 Sep 2014
    Vaginal chlorhexidine during labour for preventing maternal and neonatal infections (excluding group B streptococcal and HIV) Updated
    Bacteria live in women's vaginas and generally cause no problems. Very occasionally they infect the placenta during labour and can pass to the baby, causing an infection. These infections can occasionally make the baby very ill and very occasionally the baby might die. The review of three trials (3012 participants) found there was not enough information ...
  4. 11 Sep 2014
    Artemether injection for treating people with severe malaria New
    In this review, researchers from The Cochrane Collaboration examined the effects of treating people that have severe malaria with artemether injected intramuscularly, and compared it to treatment with other antimalarial drugs given intramuscularly or intravenously. After searching for relevant trials up to 9 April 2014, we included 18 randomized controlled ...
  5. 9 Sep 2014
    Haemophilus influenzae oral vaccination for preventing acute exacerbations of chronic bronchitis and chronic obstructive pulmonary disease New
    Review question We reviewed the evidence about the effect of a non-typeable Haemophilus influenzae (H. influenzae) (NTHi) vaccine in preventing repeated H. influenzae infections in people with chronic obstructive pulmonary disease (COPD) or chronic bronchitis. Background People with COPD can often have frequent infections that worsen symptoms of ...
  6. 1 Sep 2014
    No recommendations regarding type of wound dressing for the prevention of surgical site infection Updated
    Millions of surgical procedures are conducted globally each year. The majority of procedures result in wounds in which the edges are brought together to heal using stitches, staples, clips or glue - this is called 'healing by primary intention'. Afterwards, wounds are often covered with a dressing that acts as a barrier between them and the outside ...
  7. 31 Aug 2014
    Treatment of severe or progressive Kaposi's sarcoma in HIV-infected adults
    Kaposi’s sarcoma was the first tumor to be described in association with HIV infection and is an AIDS-defining condition. It is also known as Kaposi's sarcoma-associated herpes virus (KSHV) as Herpes virus 8 (HHV8) is recognized as an essential and necessary factor in the pathogenesis of KS. Nonetheless, not all HHV-8-infected individuals will develop ...
  8. 28 Aug 2014
    Systematic review of randomised controlled trials about the efficacy and safety of colchicine in people with pericarditis New
    Pericarditis is the inflammation and swelling of the tissue covering the outer layer of the heart. Pericarditis causes severe and disabling chest pain and fever, however the main issue is the repeated recurrence of pericarditis attacks. Colchicine is an ancient medication that has been used in the treatment of other inflammatory diseases such as gout. We ...
  9. 6 Aug 2014
    Drugs for treating urinary schistosomiasis Podcast Updated
    What is urinary schistosomiasis and how is it treated? Urinary schistosomiasis is a disease caused by infection of people with the parasitic worm Schistosoma haematobium. These worms live in blood vessels around the infected person's bladder and the worm releases eggs which are released in the person's urine. If the urine is passed into ponds or lakes, ...
  10. 5 Aug 2014
    Pneumococcal vaccines for children and adults with cystic fibrosis Updated
    Cystic fibrosis is an inherited disease which causes mucus in the lungs to be more sticky than normal, leading to frequent lung infections and lung damage. Pneumococcus is a type of bacteria that can cause infection throughout the body, including in the urine, blood stream, fluid around the brain and in the lungs. These infections can be very serious ...

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