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  1. 7 Jul 2014
    Interventions to increase influenza (flu) vaccination uptake for people aged 60 and older Updated
    Many health authorities recommend influenza vaccination of older people. However, vaccination uptake in people aged 60 and older varies across countries, socioeconomic and health-risk groups. It is important to identify effective interventions to increase influenza vaccination uptake. We included 57 randomised controlled trials (RCTs) with 896,531 participants ...
  2. 1 Jul 2014
    Shifting HIV care from doctors to non-doctors to improve access to therapy for people living with HIV
    Background High levels of healthcare worker shortage has limited HIV infected patients access to antiretroviral therapy in lower and middle-income countries. This occurs most where the burden of HIV disease is greatest and where access to trained doctors is limited. We wanted to assess if task shifting of care from doctors to non-doctors provides ...
  3. 30 Jun 2014
    A single dose of primaquine added to malaria treatment to prevent malaria transmission Updated
    We conducted a review of the effects of adding a single dose (or short course) of primaquine to malaria treatment with the aim of reducing the transmission of malaria. We included 17 randomized controlled trials and one quasi-randomized controlled trial. What is primaquine and how might it reduce transmission Primaquine is an antimalarial drug which ...
  4. 30 Jun 2014
    Corticosteroids for treating dengue infection in children and adults Updated
    Dengue is a disease caused by a virus transmitted by mosquitoes, occurring in many resource-limited countries, and children are often most severely affected. Most infected patients will recover with mild symptoms, but a few progress to severe dengue and may die. There is no specific treatment for dengue, but some clinicians provide corticosteroids at ...
  5. 29 Jun 2014
    Zinc supplements for preventing middle ear infections Updated
    Background Middle ear infections are common, especially among young children, usually causing earache and some temporary (occasionally permanent) hearing loss. Zinc is an essential micronutrient, which has a role in the optimal functioning of the immune system and resistance to infection. It must be consumed regularly as it cannot be stored in the ...
  6. 23 Jun 2014
    Post-exposure prophylaxis vaccine to prevent varicella (chickenpox)
    Review question This review assessed how useful the varicella (also known as chickenpox) vaccine is in preventing chickenpox when given to children or adults who have never been immunised or previously had chickenpox, but who receive the vaccine within a short time following exposure to a person infectious with chickenpox. Varicella is a highly contagious ...
  7. 20 Jun 2014
    Rapid diagnostic tests for visceral leishmaniasis New
    Visceral leishmaniasis (or kala-azar) is caused by a parasite, results in fever, a large spleen and other health problems, occuring in India, Bangladesh and Nepal, east Africa, the Mediterranean region and Brazil. Without treatment people die, and proper treatment can result in cure, so diagnosis is important. Many of the tests that are used to determine ...
  8. 19 Jun 2014
    Antibiotics for treating cholera New
    Cochrane Collaboration researchers conducted a review of the effects of antibiotics for treating people with cholera. After searching for relevant trials, they included 39 randomized controlled trials enrolling 4623 people with cholera. What is cholera and how might antibiotics work Cholera is a form of severe watery diarrhoea, which spreads from ...
  9. 17 Jun 2014
    Bronchodilators for bronchiolitis for infants with first-time wheezing Updated
    What is bronchiolitis? Bronchiolitis is an acute, highly contagious, viral infection of the lungs that is common in infants 0 to 12 months of age. It occurs every year in the winter months. It causes the small airways in the lungs to become inflamed and fill with debris. The airways are narrowed and this leads to blocking of the free passage of air. ...
  10. 17 Jun 2014
    Aminoadamantanes versus other antiviral drugs for chronic hepatitis C New
    Background Hepatitis C virus is mainly transmitted by contact to infected blood. Chronic hepatitis C infection affects around 3% of the world population and progresses slowly. Most patients present without symptoms, or with symptoms like fatigue or liver-related morbidity. Frequently, the disease is discovered by coincidence because of abnormal laboratory ...

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