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  1. 18 Sep 2014
    Influence of beta-blockers on perioperative adverse events
    Any type of surgery is associated with an increased stress response, which can make the body vulnerable to untoward outcomes. These outcomes may range from death to a heart attack and rhythm disturbances to heart failure, stroke and the like. Beta-blockers are drugs that attenuate this stress response, which results in slowing down of heart rate and ...
  2. 26 May 2014
    Psychological treatments to reduce pain in people undergoing open heart surgery
    Acute postoperative pain is one of the most disturbing complaints in open heart surgery, and is related to a risk of negative consequences such as impaired wound healing, chronic pain or depression. Psychological treatment is designed to improve patients' knowledge and to alter surgery-related mental distress, negative beliefs and non-compliance. It ...
  3. 7 Feb 2014
    Blood transfusions in patients with heart problems requiring surgery on their heart
    This review aims to determine the current evidence on the impact of red blood cell transfusion on patients born with heart problems undergoing heart surgery. Background Between four and nine children out of every 1000 born alive have hearts that have not formed properly. Heart surgery may allow a child to live and grow or may correct the defect in ...
  4. 23 Jul 2013
    Preoperative statin therapy for patients undergoing cardiac surgery
    Cardiac surgery offers a highly efficient therapeutic option to patients with heart disease, but bears at the same time a significant risk of the development of post-operative adverse events. Despite the increasing proportion of patients referring to cardiac surgery with major comorbidities, the operative results have remained stable during the past ...
  5. 6 Jun 2013
    Epidural analgesia for heart surgery
    The use of thoracic epidural analgesia (TEA) in heart surgery is controversial. TEA produces a high level of pain relief and may reduce some of the adverse effects that are associated with heart surgery. Along with these potential benefits of TEA there is a widespread fear that TEA could cause bleeding into the epidural space (haematoma). We have conducted ...
  6. 28 Feb 2013
    People who undergo bypass surgery for narrowed coronary vessels may be less likely to need re-intervention than those treated using angioplasty with stents
    Narrowing of coronary arteries can be alleviated by complete replacement using bypass surgery or, alternatively, unblocking and supporting the vessels open using angioplasty and stents. Analysis of RCTs to 2004 indicates re-intervention (to alleviate subsequent narrowing) is needed less commonly after surgery than after stenting. Risk of death or heart ...
  7. 31 Jan 2013
    There is not enough evidence to show that lowering body temperature can reduce nerve damage during coronary artery bypass surgery.
    For people with severe coronary artery (heart) disease, bypass surgery can be life saving. However, bypass surgery is sometimes associated with neurological complications, where very occasionally patients may suffer a stroke, or more commonly memory or personality may be affected. The temperature used during bypass surgery may influence these adverse ...
  8. 31 Jan 2013
    Intervention is favored in the prevention of post-operative atrial fibrillation after heart surgery
    Atrial fibrillation after heart surgery is a common complication that has been associated with poor outcomes. We reviewed the literature to better understand the role of preventative interventions for this condition. By combining the results of 118 studies with 17,364 participants, we are able to gain a better understanding of the evidence behind each ...
  9. 14 Nov 2012
    Preoperative physical therapy for elective cardiac surgery patients
    Patients undergoing cardiac surgery are at risk of postoperative pulmonary complications such as pneumonia. These complications prolong postoperative recovery and may even lead to death. Increased physical fitness improves people's functional capacity, including their lungs, and could result in individuals being better prepared to withstand the consequences ...
  10. 12 Sep 2012
    The use of incentive spirometry for preventing pulmonary complications in adults people undergoing coronary artery bypass graft surgery
    Breathing complications after coronary artery bypass graft (CABG) surgery increases hospital stay and is with associated high healthcare costs. CABG may interfere with the lungs, causing sections of them to collapse which may lead to pneumonia. Re-inflating areas of the collapsed lung may be done by a device - an incentive spirometer - that reinforces ...

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