Cochrane Summaries

Independent high-quality evidence for health care decision making

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  1. Apr 2013
    Steroids applied directly to polyps in the nose in people with cystic fibrosis Updated
    People with cystic fibrosis often have polyps in their nose which can cause discharge from the nose and block it up. We know that people with cystic fibrosis who have polyps in their nose also have more of some types of bacteria in their lungs. This can lead to serious chest complications later on. If we treat the polyps effectively at an early stage, ...
  2. Jan 2013
    Vitamin C for preventing and treating the common cold Podcast
    The common cold is a major cause of visits to a doctor in high-income countries and of absenteeism from work and school. There are over 200 viruses which can cause the common cold symptoms including runny nose, congestion, sneezing, sore throat, cough, and sometimes headache, fever and red eyes. Symptoms vary from person to person and cold to cold. ...
  3. Dec 2012
    Topical corticosteroids for nasal polyps
    This review summarises the evidence for the effects of corticosteroids being delivered into the nose by spray (topical delivery) as part of the management of nasal polyps. Nasal polyps develop as a result of chronic inflammation of the mucous lining of the nose and sinuses and they can cause nasal obstruction, poor sinus drainage, loss of smell/taste, ...
  4. Oct 2012
    Steroids for the common cold
    Although there are a number of medications (including many over-the-counter) used to help improve the symptoms of the common cold, none have good evidence of benefit. Steroids (corticosteroids) have been shown to help relieve symptoms in other types of upper respiratory tract infections by reducing the inflammation of the lining of the nose and throat, ...
  5. Oct 2012
    Antibiotics for clinically diagnosed acute rhinosinusitis in adults
    Acute rhinosinusitis is a common condition that involves blockage of the nose passage and mucus in the sinuses. The diagnosis of acute rhinosinusitis in this review is based on clinical symptoms only, i.e. purulent discharge from the nose or other rhinosinusitis-like symptoms, such as unilateral facial pain or pressure, pain when bending forward, pain ...
  6. Sep 2012
    Decongestants, antihistamines and nasal irrigation for acute sinusitis in children
    Young children experience an average of six to eight colds per year. Out of every 10 children with a cold, one develops sinusitis. Sinusitis occurs when the sinuses, which do not drain properly during a cold, become secondarily infected with bacteria. Instead of getting better, children with sinusitis often have worsening or persistent cold symptoms. ...
  7. Sep 2012
    Interventions for recurrent nosebleeds of unknown cause in children
    Nosebleeds in children usually just stop by themselves or after pinching the nose. However, some children get repeated nosebleeds with no specific cause (recurrent idiopathic epistaxis). The most common treatments are cautery or antiseptic cream, or both. Cautery (a method of sealing) can be painful even with local anaesthetic, and usually involves ...
  8. Aug 2012
    Over-the-counter (OTC) medications for acute cough in children and adults in ambulatory settings
    Acute cough is a common and troublesome symptom in people who suffer from acute upper respiratory tract infection. Many people self prescribe over-the-counter (OTC) cough preparations and health practitioners often recommend their use for the initial treatment of cough. Twenty-six trials involving 4037 people were included. The results of this review ...
  9. May 2012
    Zinc for the common cold
    The common cold is often caused by the rhinovirus. It is one of the most widespread illnesses and is a leading cause of visits to the doctor and absenteeism from school and work. Complications of the common cold include otitis media (middle ear infection), sinusitis and exacerbations of reactive airway diseases. There is no proven treatment for the ...
  10. Apr 2012
    Helminth therapy (worms) for allergic rhinitis Podcast
    Allergic rhinitis is a common health problem affecting about 500 million people worldwide; its prevalence is increasing. The symptoms of allergic rhinitis include sneezing, and an itchy, runny and blocked nose. Several classes of drugs are used to treat allergic rhinitis, but these drugs may be ineffective, and some drug classes have side effects after ...

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