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  1. 10 Apr 2014
    Regulatory information on trials of oseltamivir (Tamiflu) and zanamivir (Relenza) for influenza in adults and children Podcast Updated
    Oseltamivir and zanamivir have been stockpiled in many countries to treat and prevent seasonal and pandemic influenza, before an influenza vaccine matched to the circulating virus becomes available. Oseltamivir is classified by the World Health Organization as an essential medicine. How this review has been approached We have updated and combined ...
  2. 9 Apr 2014
    Drugs to control the movement of salt in the lungs of people with cystic fibrosis Updated
    Usually salt is absorbed from liquid on the surface of the lungs to stop fluid building up there. In cystic fibrosis too much salt is absorbed and there is little liquid left on the airway surfaces. As a result people with cystic fibrosis have problems clearing their lungs of sticky secretions. Thus the lungs are left open to infection. Drugs applied ...
  3. 2 Apr 2014
    Antibiotic treatment for Stenotrophomonas maltophilia in people with cystic fibrosis Updated
    Stenotrophomonas maltophilia is a bacteria which is resistant to several antibiotics. Over the last 10 years this bacteria has increasingly been found in the lungs of people with cystic fibrosis. Chronic infection with Stenotrophomonas maltophilia has been found to be linked to pulmonary infections. However, at present, it is unclear if people with ...
  4. 1 Apr 2014
    Antibodies for preventing measles after exposure New
    People who have had measles, or measles vaccine, have antibodies against the virus in their blood that protect them from developing measles should they come into contact with it. These antibodies can be extracted from blood donated by these individuals. If people without antibodies come into contact with someone who is contagious with measles, they ...
  5. 25 Mar 2014
    Steroidal anti-inflammatory medication given by mouth or injection for acute sinusitis Updated
    Review question We reviewed the evidence about the effect of steroidal anti-inflammatory medication (i.e. corticosteroids) given by mouth or injection (i.e. systemically) compared to placebo or standard clinical care on acute attacks of nose and sinus complaints (i.e. acute sinusitis) in children and adults. Background Acute sinusitis may be caused ...
  6. 11 Mar 2014
    Over-the-counter medications to help reduce cough for children and adults on antibiotics for acute pneumonia Updated
    There are many causes of acute cough, one of which is pneumonia. Cough is burdensome and impairs quality of life. Over-the-counter (OTC) medications are commonly purchased and used by patients, and are recommended by healthcare staff as additional medications in the treatment of pneumonia. There are many classes of OTC medications for cough, such as ...
  7. 10 Mar 2014
    Do inhaled steroids increase the risk of pneumonia in people with chronic obstructive pulmonary disease (COPD)? New
    Why is this question important? Inhaled corticosteroids (ICS) are drugs that can reduce the occurrence of COPD flare-ups and improve quality of life. In COPD, ICS are commonly used alongside long-acting beta2-agonists (LABA). The most common combinations of ICS and LABA inhalers are fluticasone and salmeterol, and budesonide and formoterol, but fluticasone ...
  8. 6 Mar 2014
    Vaccines for preventing influenza in people with cystic fibrosis Updated
    People with cystic fibrosis have blocked airways which results in frequent airway infections. Infections with viral diseases like influenza ("the flu") can worsen lung damage. Doctors therefore often advise people with cystic fibrosis to be vaccinated against influenza every year. We searched for studies which compared different vaccines or compared ...
  9. 1 Mar 2014
    Can interventions for parents and people caring for children reduce children's exposure to tobacco smoke
    Background Children exposed to cigarette smoke (environmental tobacco smoke) are at greater risk of lung problems, infections and serious complications including sudden infant death syndrome. Preventing exposure to cigarette smoke in infancy and childhood might therefore significantly improve children's health worldwide. Parental smoking is a common ...
  10. 20 Feb 2014
    Echinacea for preventing and treating the common cold Podcast
    Preparations of the plant Echinacea are widely used in some European countries and in North America for common colds. Echinacea preparations available on the market differ greatly as different types (species) and parts (herb, root or both) of the plant are used, different manufacturing methods (drying, alcoholic extraction or pressing out the juice ...

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