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  1. 21 Nov 2014
    Amantadine and rimantadine to prevent and treat influenza A in children and the elderly Updated
    Review question As recommended by the World Health Organization (WHO), oseltamivir (Tamiflu) is currently used for people with influenza A. In previous pandemics, the virus was susceptible to amantadine and rimantadine. If they are safe and the circulating strain proves to be susceptible to these drugs, they could be an alternative for managing influenza. ...
  2. 18 Nov 2014
    Reminder systems to improve patient attendance at tuberculosis clinics Updated
    This Cochrane Review summarizes trials evaluating the effects of reminder systems on attendance at tuberculosis (TB) clinics and completion of TB treatment. After searching for relevant trials up to 29 August 2014, we included nine trials, including 4654 people. What are reminder systems and how might they help? Effective treatment for TB requires ...
  3. 11 Nov 2014
    Garlic for the common cold Podcast Updated
    Background Garlic is popularly believed to be useful for the common cold. This belief is based on traditional use and some laboratory evidence that garlic has antibacterial and antiviral properties. On average, adults have two to four common colds per year. Study characteristics The evidence is current to the 7 August 2014. Of the eight studies ...
  4. 10 Nov 2014
    Different ways of giving antibiotics to eradicate Pseudomonas aeruginosa infection in people with cystic fibrosis Updated
    Review question We reviewed the evidence for the effectiveness of antibiotics in getting rid of a lung infection with a germ called Pseudomonas aeruginosa in people with cystic fibrosis. Background Cystic fibrosis is an inherited condition where the airways often become blocked with mucus. It is associated with chest infections, which can lead to ...
  5. 6 Nov 2014
    Use of rapid point-of-care testing for infection to guide doctors prescribing antibiotics for acute respiratory infections in primary care settings New
    Review question We reviewed the evidence of the effect and safety of a rapid test of infection at point-of-care for using antibiotics in people with acute respiratory infections (ARIs) (e.g. common colds) in primary care. Background Antibiotic treatment is common in ARIs despite the fact that the vast majority are caused by viruses, against which ...
  6. 3 Nov 2014
    Use of oral supplements to increase calorie intake in people with cystic fibrosis Updated
    We reviewed the evidence for the use of oral supplements to increase calorie intake in people with cystic fibrosis. Background Cystic fibrosis affects many organs, including the digestive system, and can lead to food not being absorbed as it should be, which in turn leads to growth problems. Children with cystic fibrosis need more energy than ...
  7. 27 Oct 2014
    Decongestants, antihistamines and nasal irrigation for acute sinusitis in children Updated
    Review question The goal of this review was to determine whether there is any evidence in the medical literature for or against the use of decongestants, antihistamines and nasal irrigation for acute sinusitis in children. Background Young children experience an average of six to eight colds per year. Out of every 10 children with a cold, one develops ...
  8. 24 Oct 2014
    Treatments to cure long-term infections with Burkholderia cepacia in people with cystic fibrosis New
    Review question We reviewed the evidence for antibiotic treatment to cure early infection with Burkholderia cepacia complex in people with cystic fibrosis and prevent it becoming permanent. Background Cystic fibrosis is an inherited disease and people who have this disease produce large amounts of thick mucus which is difficult to clear. This mucus ...
  9. 19 Oct 2014
    Non-drug management of breathing problems for children with severe physical and intellectual impairment New
    Background For a variety of reasons, some children live with very severe intellectual and physical problems; they are unable to walk or talk and require a lot of care. In this study we refer to them as children with severe global developmental delay (SGDD); this is not a specific diagnosis but is rather an 'umbrella term' used to describe a group of ...
  10. 9 Oct 2014
    Antibiotics for bronchiolitis in children under two years of age Updated
    Question We reviewed the evidence on the effect of antibiotics on clinical outcomes in children with bronchiolitis. Background Bronchiolitis is a serious respiratory illness that affects babies. It is most commonly caused by respiratory syncytial virus (RSV) and is the most common reason for hospitalisation in babies younger than six months. Babies ...

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