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  1. 14 Dec 2014
    Surfactant for meconium aspiration syndrome in term and late preterm infants Updated
    Lay title: Surfactant treatment for infants who have inhaled meconium into the lungs in or around the time of birth Review question: Does the administration of surfactant improve lung function and lead to better clinical outcomes in infants born at or near term who have inhaled meconium in or around the time of birth? Background: The lungs of newborn ...
  2. 10 Dec 2014
    Oxygen therapy as part of the treatment for respiratory infections in children Updated
    Review question We reviewed the evidence about the beneficial effect of oxygen supplementation therapy as part of the treatment for children with acute lower respiratory tract infection (LRTI). As oxygen may be administered using different delivery methods, we reviewed the most commonly used methods to deliver oxygen in children. As a secondary question, ...
  3. 9 Dec 2014
    Vitamin E supplementation in people with cystic fibrosis New
    Review question We wanted to know what effects, if any, vitamin E supplementation (at any dose) has on how often people with cystic fibrosis have health problems due to vitamin E deficiency. Background Approximately 85% to 90% of people with cystic fibrosis do not produce enough enzymes in their pancreas and are not able to absorb fat when digesting ...
  4. 3 Dec 2014
    Antibiotic treatment for nontuberculous mycobacteria in people with cystic fibrosis  Updated
    Nontuberculous mycobacteria are bacteria that are in the same family as tuberculosis and are commonly found in the soil and water. These bacteria can be found in the lungs of people with cystic fibrosis and can cause their lung function to worsen. Although there are guidelines on which antibiotics to use to treat lung infection due to these bacteria, ...
  5. 28 Nov 2014
    Treatments to fight fungal infections which cause allergic bronchopulmonary aspergillosis in people with cystic fibrosis Updated
    Review question We planned to review evidence about the effect of treatments to fight fungal infections which cause allergic bronchopulmonary aspergillosis in people with cystic fibrosis. Background Allergic bronchopulmonary aspergillosis (ABPA) is an allergic lung reaction to a type of fungus (usually Aspergillus fumigatus) in some people with ...
  6. 24 Nov 2014
    Pentoxifylline for the prevention of bronchopulmonary dysplasia in preterm infants New
    Babies who are born early (preterm) often suffer from long-lasting breathing problems known as bronchopulmonary dysplasia, which can lead to poor health in childhood and adulthood. Drugs that act on the body's self-defense system may help to lower the risk of long-lasting breathing problems. Pentoxifylline is one such drug. The main aim of this review ...
  7. 24 Nov 2014
    Giving antibiotics regularly to people with cystic fibrosis to prevent infection with a germ called Staphylococcus aureus Updated
    Review question We reviewed the evidence about the benefits and adverse effects of giving regular antibiotics to people with cystic fibrosis to prevent infection with a germ called Staphylococcus aureus. Background Cystic fibrosis blocks the airways with mucus and causes frequent airway infections. These can lead to death from breathing failure. ...
  8. 24 Nov 2014
    Over-the-counter (OTC) medications for acute cough in children and adults in community settings Updated
    Review question We undertook a review to determine the effectiveness of over-the-counter cough medicines in reducing cough in children and adults in community settings. We found 29 trials involving 4835 people. Background Acute cough is a common and troublesome symptom in children and adults suffering from acute upper respiratory tract infection ...
  9. 21 Nov 2014
    Amantadine and rimantadine to prevent and treat influenza A in children and the elderly Updated
    Review question As recommended by the World Health Organization (WHO), oseltamivir (Tamiflu) is currently used for people with influenza A. In previous pandemics, the virus was susceptible to amantadine and rimantadine. If they are safe and the circulating strain proves to be susceptible to these drugs, they could be an alternative for managing influenza. ...
  10. 18 Nov 2014
    Reminder systems to improve patient attendance at tuberculosis clinics Updated
    This Cochrane Review summarizes trials evaluating the effects of reminder systems on attendance at tuberculosis (TB) clinics and completion of TB treatment. After searching for relevant trials up to 29 August 2014, we included nine trials, including 4654 people. What are reminder systems and how might they help? Effective treatment for TB requires ...

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