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  1. 24 Nov 2014
    Pentoxifylline for the prevention of bronchopulmonary dysplasia in preterm infants New
    Babies who are born early (preterm) often suffer from long-lasting breathing problems known as bronchopulmonary dysplasia, which can lead to poor health in childhood and adulthood. Drugs that act on the body's self-defense system may help to lower the risk of long-lasting breathing problems. Pentoxifylline is one such drug. The main aim of this review ...
  2. 24 Nov 2014
    Over-the-counter (OTC) medications for acute cough in children and adults in community settings Updated
    Review question We undertook a review to determine the effectiveness of over-the-counter cough medicines in reducing cough in children and adults in community settings. We found 29 trials involving 4835 people. Background Acute cough is a common and troublesome symptom in children and adults suffering from acute upper respiratory tract infection ...
  3. 24 Nov 2014
    Giving antibiotics regularly to people with cystic fibrosis to prevent infection with a germ called Staphylococcus aureus Updated
    Review question We reviewed the evidence about the benefits and adverse effects of giving regular antibiotics to people with cystic fibrosis to prevent infection with a germ called Staphylococcus aureus. Background Cystic fibrosis blocks the airways with mucus and causes frequent airway infections. These can lead to death from breathing failure. ...
  4. 21 Nov 2014
    Amantadine and rimantadine to prevent and treat influenza A in children and the elderly Updated
    Review question As recommended by the World Health Organization (WHO), oseltamivir (Tamiflu) is currently used for people with influenza A. In previous pandemics, the virus was susceptible to amantadine and rimantadine. If they are safe and the circulating strain proves to be susceptible to these drugs, they could be an alternative for managing influenza. ...
  5. 18 Nov 2014
    Reminder systems to improve patient attendance at tuberculosis clinics Updated
    This Cochrane Review summarizes trials evaluating the effects of reminder systems on attendance at tuberculosis (TB) clinics and completion of TB treatment. After searching for relevant trials up to 29 August 2014, we included nine trials, including 4654 people. What are reminder systems and how might they help? Effective treatment for TB requires ...
  6. 11 Nov 2014
    Garlic for the common cold Updated
    Background Garlic is popularly believed to be useful for the common cold. This belief is based on traditional use and some laboratory evidence that garlic has antibacterial and antiviral properties. On average, adults have two to four common colds per year. Study characteristics The evidence is current to the 7 August 2014. Of the eight studies ...
  7. 10 Nov 2014
    Different ways of giving antibiotics to eradicate Pseudomonas aeruginosa infection in people with cystic fibrosis Updated
    Review question We reviewed the evidence for the effectiveness of antibiotics in getting rid of a lung infection with a germ called Pseudomonas aeruginosa in people with cystic fibrosis. Background Cystic fibrosis is an inherited condition where the airways often become blocked with mucus. It is associated with chest infections, which can lead to ...
  8. 6 Nov 2014
    Use of rapid point-of-care testing for infection to guide doctors prescribing antibiotics for acute respiratory infections in primary care settings New
    Review question We reviewed the evidence of the effect and safety of a rapid test of infection at point-of-care for using antibiotics in people with acute respiratory infections (ARIs) (e.g. common colds) in primary care. Background Antibiotic treatment is common in ARIs despite the fact that the vast majority are caused by viruses, against which ...
  9. 3 Nov 2014
    Use of oral supplements to increase calorie intake in people with cystic fibrosis Updated
    We reviewed the evidence for the use of oral supplements to increase calorie intake in people with cystic fibrosis. Background Cystic fibrosis affects many organs, including the digestive system, and can lead to food not being absorbed as it should be, which in turn leads to growth problems. Children with cystic fibrosis need more energy than ...
  10. 27 Oct 2014
    Decongestants, antihistamines and nasal irrigation for acute sinusitis in children Updated
    Review question The goal of this review was to determine whether there is any evidence in the medical literature for or against the use of decongestants, antihistamines and nasal irrigation for acute sinusitis in children. Background Young children experience an average of six to eight colds per year. Out of every 10 children with a cold, one develops ...

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