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  1. 1 Jul 2014
    Drugs to prevent hearing loss in children receiving platinum chemotherapy for cancer
    Platinum-based chemotherapy, including cisplatin, carboplatin and/or oxaliplatin, is used in the treatment of different types of childhood cancer. Unfortunately, one of the most important adverse effects of platinum chemotherapy is hearing loss. This can occur not only during treatment but also years after the end of treatment. Although hearing loss ...
  2. 29 Jun 2014
    Zinc supplements for preventing middle ear infections
    Background Middle ear infections are common, especially among young children, usually causing earache and some temporary (occasionally permanent) hearing loss. Zinc is an essential micronutrient, which has a role in the optimal functioning of the immune system and resistance to infection. It must be consumed regularly as it cannot be stored in the ...
  3. 26 Jun 2014
    Different infusion durations for preventing platinum-induced hearing loss in children with cancer
    Platinum-based chemotherapy, including cisplatin, carboplatin or oxaliplatin, or a combination of these, is used to treat different types of childhood cancer. Unfortunately, one of the most important adverse effects of platinum chemotherapy is hearing loss. This can occur not only during treatment but also years after the end of treatment. Although ...
  4. 5 Jun 2014
    Photodynamic therapy for recurrent respiratory papillomatosis
    Background Recurrent respiratory papillomatosis is a condition of the mucosal lining of the upper airway, which leads to multiple benign, wart-like growths (papilloma). Although not cancerous, it can lead to serious problems, including hoarseness and airway obstruction. The main treatment is repeated surgical removal of the papilloma using a laser ...
  5. 2 Apr 2014
    Vaccination against a bacterium called pneumococcus for preventing middle ear infection
    Review question We reviewed the evidence about the effect of vaccination against pneumococcus (a type of bacterium) on preventing middle ear infections in children. Background Middle ear infection, or otitis media, is one of the most common respiratory infections in childhood. Infection with Streptococcus pneumoniae (pneumococcus) is a frequent cause ...
  6. 12 Mar 2014
    Auditory-verbal therapy for promoting spoken language development in children with permanent hearing impairments
    Permanent hearing impairment greatly restricts a child's speech and language development and hinders his or her behavioural, cognitive and social functioning. Although technological devices, such as hearing aids and cochlear implants, enable the child to hear spoken words, they fail to teach the child how to listen, how to process language or how to ...
  7. 20 Feb 2014
    Echinacea for preventing and treating the common cold Podcast
    Preparations of the plant Echinacea are widely used in some European countries and in North America for common colds. Echinacea preparations available on the market differ greatly as different types (species) and parts (herb, root or both) of the plant are used, different manufacturing methods (drying, alcoholic extraction or pressing out the juice ...
  8. 13 Dec 2013
    Dosage intervals of amoxicillin for the treatment of acute middle ear infection
    Acute middle ear infection (acute otitis media) is a very common disease in children and may cause pain and hearing loss. Delayed or ineffective treatment may lead to serious complications such as ear drum perforation, sensorineural hearing loss or the disease becoming chronic. Amoxicillin, with or without clavulanate, is the most commonly used antibiotic ...
  9. 5 Nov 2013
    Antibiotics for people with sore throats
    Question This review sought to determine whether antibiotics are effective for treating the symptoms and reducing the potential complications associated with sore throats. Background Sore throats are infections caused by bacteria or viruses. People usually recover quickly (usually after three or four days), although some develop complications. ...
  10. 10 Oct 2013
    Nebulized epinephrine for croup in children
    Croup is a common childhood illness which primarily affects those between the ages of six months and three years, with a peak annual incidence in the second year of life of nearly five per cent. Males and females are affected equally. Croup is most often caused by a viral infection. Symptoms of croup include a hoarse voice, a 'barking' cough and noisy ...

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