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  1. 1 Sep 2014
    No recommendations regarding type of wound dressing for the prevention of surgical site infection Updated
    Millions of surgical procedures are conducted globally each year. The majority of procedures result in wounds in which the edges are brought together to heal using stitches, staples, clips or glue - this is called 'healing by primary intention'. Afterwards, wounds are often covered with a dressing that acts as a barrier between them and the outside ...
  2. 31 Aug 2014
    Treatment of severe or progressive Kaposi's sarcoma in HIV-infected adults
    Kaposi’s sarcoma was the first tumor to be described in association with HIV infection and is an AIDS-defining condition. It is also known as Kaposi's sarcoma-associated herpes virus (KSHV) as Herpes virus 8 (HHV8) is recognized as an essential and necessary factor in the pathogenesis of KS. Nonetheless, not all HHV-8-infected individuals will develop ...
  3. 29 Aug 2014
    Prevention of blood clots in non-hospitalised cancer patients receiving chemotherapy Updated
    Cancer patients are more likely than patients without cancer to develop blood clots in their veins (venous thromboembolism or VTE). Chemotherapy further increases this risk. Yet bleeding at the site of the cancer and a relative decrease in the number of platelets in the blood (thrombocytopenia) that is caused by chemotherapy may make cancer patients ...
  4. 28 Aug 2014
    Treatments for acute bleeds in people with acquired hemophilia A New
    Acquired hemophilia A is a rare but severe bleeding disorder caused by the autoantibody directed against factor VIII (FVIII, a blood clotting protein) in patients with no previous history of a bleeding disorder. This bleeding disorder occurs more frequently in the elderly and may be associated with several other conditions, such as solid tumours, autoimmune ...
  5. 22 Aug 2014
    Advanced training in trauma life support for hospital staff Updated
    Training in 'advanced trauma life support' (ATLS) is increasingly used in both rich and poor countries. ATLS is intended to improve the way in which care is given to injured people, thereby reducing death and disability. Some research has been done that suggests ATLS programmes improve the knowledge of staff who have been trained, but there have been ...
  6. 21 Aug 2014
    Advanced training in trauma life support for ambulance crews Updated
    Injury is one of the top ten causes of death and disability worldwide. It results in an early loss of life for many young people and ongoing high medical care costs among survivors. Advanced life support (ALS) training for ambulance crews with emphasis on trauma is believed to have contributed to a reduction in the number of deaths from injury in predominantly ...
  7. 20 Aug 2014
    Budesonide for maintenance of remission in Crohn's disease Updated
    Budesonide is a corticosteroid drug which is rapidly broken down by the liver, reducing corticosteroid-related side effects (e.g., moon face). Research showing that budesonide is effective in treating active Crohn's disease has led to clinical trials examining the effect of budesonide on reducing disease recurrence in non-active Crohn's disease. This ...
  8. 19 Aug 2014
    Reducing unwanted movement of teeth during treatment with orthodontic braces, comparing surgically placed implants as stabilisers (anchors) with other conventional methods Updated
    Review question This review, produced by the Cochrane Oral Health Group, seeks to assess the effects of using implants surgically placed in bone in the mouth in order to stabilise (anchor) teeth during treatment with orthodontic braces and compares implants with the use of conventional methods. It also assesses the effects of different surgical anchorage ...
  9. 18 Aug 2014
    Glasses to prevent eye misalignment in far-sighted children
    Review question We compared the benefits and harms of wearing glasses to other interventions in far-sighted children to prevent the development of eye misalignment. Background Infants typically are born hyperopic, or far-sighted, and as they grow, their eyes typically grow to where they can see clearly. Some children, however, remain very far-sighted. ...
  10. 14 Aug 2014
    Urate oxidase for the prevention and treatment of complications from massive lysis (breakdown) of tumour cells in children with cancer Updated
    Tumour lysis syndrome occurs when uric acid and other cellular substances are rapidly released into the circulation when tumour cells are broken down spontaneously or during treatment. Uric acid has low solubility (does not dissolve easily); therefore, it can build up in the kidney resulting in kidney failure and possibly death eventually. Urate oxidase ...

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