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  1. 21 Jan 2015
    Different ways of Identifying women with gestational diabetes Updated
    Evidence is insufficient to permit judgement of which is the best way to identify women who have gestational diabetes. Insulin is a hormone produced in the pancreas that enables cells to absorb glucose to turn it into energy. During pregnancy, maternal resistance to insulin develops so that glucose can more easily cross the placenta to the growing foetus. ...
  2. 20 Jan 2015
    Exercise therapy for adolescents and adults with pain behind or around the kneecap (patellofemoral pain) New
    Introduction Patellofemoral pain syndrome (PFPS) is a common knee problem, which particularly affects adolescents and young adults. PFPS is characterised by retropatellar (behind the kneecap) or peripatellar (around the kneecap) pain. It is often referred to as anterior knee pain. The pain mostly occurs when load is put on the muscles that extend ...
  3. 20 Jan 2015
    Procalcitonin, C-reactive protein, and erythrocyte sedimentation rate for the diagnosis of acute pyelonephritis in children New
    In some children with urinary tract infection (UTI), the infection is localized to the bladder (lower urinary tract). In others, bacteria ascend from the bladder to the kidney (upper urinary tract). Only children with upper urinary tract involvement are at risk for developing permanent kidney damage. If non-invasive biomarkers could accurately differentiate ...
  4. 19 Jan 2015
    Complementary therapies for acne vulgaris New
    Background Acne is a chronic skin disease, which causes spots to occur simultaneously on several areas of the body, including the face, neck, back, and chest. Besides the current commonly used treatments, complementary and alternative medicines (CAM) are of increasing interest to people who often use them in addition to conventional treatments as ...
  5. 19 Jan 2015
    House dust mite reduction and avoidance measures for treating eczema New
    Background Eczema is an intensely itchy skin disease that tends to involve skin creases, such as the folds of the elbows or knees. It is a worldwide problem affecting 5% to 20% of children. Around 2% of adults have the condition, and many have a more chronic and severe form. As many as a third of people with eczema who have a positive test for allergy ...
  6. 18 Jan 2015
    Vitamin K supplementation for cystic fibrosis Updated
    Review question We reviewed the evidence to see whether supplementing vitamin K in people with cystic fibrosis counteracts the effects of deficiency on blood clotting, bone strength and quality of life in people with cystic fibrosis. We tried to determine the best dose needed to prevent this deficiency. Background Cystic fibrosis is an inherited ...
  7. 16 Jan 2015
    Haloperidol versus first-generation antipsychotics for the treatment of schizophrenia New
    Haloperidol is one of the most frequently used antipsychotic drugs worldwide. It is a first-generation antipsychotic drug. Haloperidol is highly effective in treating the ‘positive symptoms’ of schizophrenia, such as hearing voices, seeing things and having strange beliefs. However, haloperidol also has serious side effects such as involuntary shaking, ...
  8. 15 Jan 2015
    Using oxygen at high pressure (in a compression chamber) for the treatment of individuals with severe soft tissue infection (necrotizing fasciitis) New
    Severe soft tissue infection (necrotizing fasciitis) is life threatening, is associated with prolonged hospital stay and carries high risk of long-term loss of function. Routine treatment consists of immediate surgical removal of infected tissue and administration of antibiotics. Use of hyperbaric oxygen therapy, or HBOT, in addition to surgery and ...
  9. 13 Jan 2015
    Antimalarial drugs as a treatment of anaemia in children living in malaria-endemic areas. New
    Children living in malaria areas may develop severe anaemia, often caused by malaria infection, and this can cause death if not treated properly. Intermittent preventive treatment (IPT) is a course of malaria treatment given regularly to these children in order to prevent infection and malaria illness. It has been suggested that IPT could be used to ...
  10. 10 Jan 2015
    Indacaterol for the treatment of people with stable COPD New
    Review question 1. What is the effect of regular treatment with indacaterol versus no treatment on stable COPD? 2. What is the effect of regular treatment with indacaterol versus twice-daily beta2-agonists on stable COPD? Background Chronic obstructive pulmonary disease (COPD) is a progressive lung disease that causes shortness of breath and impairs ...

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