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  1. 18 Dec 2014
    Observation alone versus drain tube or needle insertion (interventional) for primary spontaneous pneumothorax in adults without previous lung disease. New
    Review question: A primary spontaneous pneumothorax (PSP) is a collection of air in the lining of the lung that occurs on its own or without a traumatic event. When this occurs, people can have chest pain and shortness of breath. Most of the time, the air in the lung is absorbed by the body and slowly decreases with time. Most of the guidelines in ...
  2. 18 Dec 2014
    Fluids for hydration in children New
    Background Many children in hospital need fluid through an intravenous line (or 'drip') because they cannot eat or drink enough and they need to remain hydrated. This fluid can cause rare but serious side effects due to the salt level in the body decreasing. When the salt level in the body decreases quickly brain swelling can occur, which can result ...
  3. 17 Dec 2014
    Medications for the treatment of cannabis dependence New
    Background Cannabis is the most common illicit drug in the world. Demand by cannabis users for treatment has been increasing in most regions of the world. Currently there are no medications specifically for the treatment of cannabis use. This review sought to assess the effectiveness and safety of medications for the treatment of cannabis dependence. Search ...
  4. 17 Dec 2014
    Ephedrine treatment for myasthenia gravis, neonatal myasthenia and congenital myasthenic syndromes New
    Review question We reviewed the evidence about the effect of ephedrine in adults and children with myasthenia gravis (MG), neonatal myasthenia and the congenital myasthenic syndromes (CMSs). Background Myasthenia is a group of rare conditions in which muscle fatigue and weakness are the main symptoms. These symptoms occur because signals do not ...
  5. 17 Dec 2014
    Graduated compression stockings for prevention of deep vein thrombosis during a hospital stay Updated
    Hospital patients can develop deep vein thrombosis (DVT) in the legs and pelvic veins immediately after surgery or if they are not mobile because of a medical illness. Symptoms vary from none to pain and swelling in the legs. A blood clot can move from the leg to the lungs, with the danger of pulmonary embolism (PE) and death. Usually the DVT clears ...
  6. 15 Dec 2014
    Glutamine supplementation for young infants with severe gastrointestinal disease Updated
    Glutamine is an amino acid that helps tissues, particularly in the gastrointestinal tract, recover from damage. We looked for evidence that giving extra glutamine to young infants with severe bowel problems helps them to recover faster and more fully. At present, only three trials are available; results suggest that supplemental glutamine has no benefit ...
  7. 15 Dec 2014
    Ursodeoxycholic acid for liver disease related to cystic fibrosis Updated
    Review question Does ursodeoxycholic acid improve measures of liver function, reduce the risk of developing chronic liver disease and improve outcomes in general in people with cystic fibrosis? Background Problems with the consistency of bile (thickened) and how it flows cause liver disease in up to 20% of young people with cystic fibrosis. Bile ...
  8. 15 Dec 2014
    Household interventions for preventing domestic lead exposure in children Podcast
    Lead poisoning is associated with adverse effects on the development and behaviour in children. Many educational and environmental household interventions to prevent lead exposure in children have been studied. This review of 14 studies found that educational and dust control interventions are not effective in reducing blood lead levels of young children. ...
  9. 14 Dec 2014
    Surfactant for meconium aspiration syndrome in term and late preterm infants Updated
    Lay title: Surfactant treatment for infants who have inhaled meconium into the lungs in or around the time of birth Review question: Does the administration of surfactant improve lung function and lead to better clinical outcomes in infants born at or near term who have inhaled meconium in or around the time of birth? Background: The lungs of newborn ...
  10. 10 Dec 2014
    Oxygen therapy as part of the treatment for respiratory infections in children Updated
    Review question We reviewed the evidence about the beneficial effect of oxygen supplementation therapy as part of the treatment for children with acute lower respiratory tract infection (LRTI). As oxygen may be administered using different delivery methods, we reviewed the most commonly used methods to deliver oxygen in children. As a secondary question, ...

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