Cochrane Summaries

Independent high-quality evidence for health care decision making

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  1. Apr 2013
    Levomepromazine for the treatment of nausea and vomiting in people with advanced disease New
    Nausea and vomiting are common and very unpleasant symptoms that are often experienced by people receiving palliative care. There are several different drug therapies which are available to treat these symptoms. Levomepromazine was originally used to treat schizophrenia but is also used to control nausea and vomiting. It can be given orally or as an ...
  2. Mar 2013
    Megestrol acetate for treatment of anorexia-cachexia syndrome
    Anorexia-cachexia syndrome (ACS) is a common clinical problem characterised by loss of appetite and weight loss. It is common in patients who suffer from advanced cancer, AIDS and some other conditions. At present, there is no cure for ACS. Megestrol acetate (MA) is classified as a female hormone and is taken by mouth. It is currently used to improve ...
  3. Mar 2013
    Multidimensional rehabilitation programmes for adult cancer survivors
    Due to improvements in detection, treatment and care an increasing number of patients are living with or surviving cancer. However, patients who survive cancer may experience a range of physical and emotional symptoms which impact on their health and quality of life. Physical symptoms may include fatigue, reduced muscle strength and weight gain, while ...
  4. Mar 2013
    Platelet transfusions, treated to reduce transfusion-transmitted infections, for the prevention of bleeding in patients with low platelet counts
    Blood for transfusion is collected from donors and then processed and stored as bags of different blood components. One of these components is platelets. Platelets are cells which help the body form clots and prevent bleeding. As for all transfusions, there are risks related to giving platelets to patients, including a small risk of transfusion-transmitted ...
  5. Mar 2013
    Spinal cord stimulation for intractable cancer-related pain
    Cancer-related pain is an emerging heavy burden on public health. Spinal cord stimulation (SCS) is a minimally invasive and potentially effective tool against chronic pain.This systematic review intended to evaluate the efficacy and effectiveness of SCS for cancer-related pain compared with standard care using conventional analgesic medication. No randomised ...
  6. Feb 2013
    Effectiverness of epidural, subarachnoid and intracerebroventricular opioid drugs to treat patients with pain due to cancer
    Cancer patients who do not obtain pain relief from treatment with opioids administered by mouth, rectally or by injection may do so if the drugs are administered in other ways. This review compared three alternative routes: intracerebroventricular (where opioids are injected through a small hole bored into the skull); epidural (where opioids are introduced ...
  7. Jan 2013
    Interventions for treating persistent and intractable hiccups in adults.
    Hiccups involve repeated, involuntary contractions of the muscles used for breathing. They usually stop of their own accord; rarely, however, they may last for more than 48 hours. When they do persist, hiccups can cause a patient considerable upset, interfere with sleeping and eating, and can lead to other complications. Many different drugs and non-drug ...
  8. Jan 2013
    Muscle stimulation for weakness in adults with advanced disease
    Individual studies suggest that the use of neuromuscular electrical stimulation, or NMES, may help improve muscle weakness which occurs as a consequence of a progressive disease. NMES uses a lightweight stimulator unit and skin electrodes to produce a muscle contraction. Being a passive form of exercise, it allows patients to exercise their leg muscles ...
  9. Jan 2013
    Multidisciplinary rehabilitation for brain tumours
    People with brain tumours may experience a range of symptoms and disabilities such as psychological problems, difficulties with mobility or self-care, and relationship and work issues, which can have a substantial impact on their quality of life.  These symptoms and disabilities may be addressed through “multidisciplinary rehabilitation” delivered by ...
  10. Jan 2013
    Multidisciplinary rehabilitation for follow-up of women treated for breast cancer
    Breast cancer is the most common cancer in women worldwide. The majority of women diagnosed with breast cancer undergo treatment involving surgery and radiotherapy or chemotherapy, or both. With these major advances in breast cancer management, many patients still have to deal with short or long-term side effects and psychological distress related to ...

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