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  1. 19 Sep 2014
    Intracystic bleomycin for children with cystic craniopharyngiomas Updated
    Craniopharyngiomas are rare, slow-growing, benign tumours in the hypothalamic-pituitary region of the brain. Although they are benign, i.e. the tumour lacks the ability to invade neighboring tissue or metastasise, there is considerable morbidity and disability even when the tumour can be resected completely. Cystic craniopharyngiomas are the commonest ...
  2. 19 Sep 2014
    Codeine, alone and with paracetamol (acetaminophen), for cancer pain New
    Codeine is an opioid medication commonly used worldwide to treat pain including cancer pain. Oral codeine, either alone or in combination with paracetamol, provided good pain relief for some people with cancer pain, based on limited amounts of information. In this review we set out to estimate how well codeine worked, how many people had side effects, ...
  3. 17 Sep 2014
    Antigen-specific active immunotherapy for ovarian cancer Updated
    Background Ovarian cancer is the leading cause of death from gynaecological cancers. Standard therapy consists of surgery and chemotherapy. Responses to chemotherapy are generally good, however, the majority of women will relapse, for which no curative treatment is available. The presence of certain immune cells in tumours is associated with longer ...
  4. 8 Sep 2014
    Evaluation of follow-up strategies for patients with epithelial ovarian cancer following completion of primary treatment Updated
    Ovarian cancer is the sixth most common cancer and seventh commonest cause of cancer death in women worldwide. Traditionally, many people who have been treated for cancer undergo long-term follow-up in a hospital outpatient setting. However, it has been suggested that the use of routine review (check-ups) may not result in women with ovarian cancer ...
  5. 8 Sep 2014
    Vaginal dilator therapy for women receiving pelvic radiotherapy Updated
    Background Pelvic radiotherapy for gynaecological (uterine, cervical, vaginal) and anorectal cancer may damage the vagina. It may cause the vagina to shrink and can make the sides stick together. It has become established practice to recommend regular vaginal dilation after radiotherapy to reduce or prevent this risk. Dilation involves inserting and ...
  6. 4 Sep 2014
    Prevention of fungal infections in patients with cancer with amphotericin B Updated
    Patients with cancer who are treated with chemotherapy or receive a bone marrow transplant have an increased risk of acquiring fungal infections. Such infections can be life-threatening. Antifungal drugs are therefore often given prophylactically to such patients, or when they have a fever. The review found that lipid formulations of amphotericin B ...
  7. 4 Sep 2014
    Prevention of fungal infections in cancer patients with amphotericin B or fluconazole Updated
    Cancer patients treated with chemotherapy or who receive a bone marrow transplant have an increased risk of acquiring fungal infections. Such infections can be life-threatening. Antifungal drugs are therefore often given prophylactically to such patients, or when they have a fever. The review could not detect a difference in effect between amphotericin ...
  8. 4 Sep 2014
    Prevention and treatment of fungal infections with nystatin in severely immunodepressed patients Updated
    People on chemotherapy for cancer, receiving a transplant or with AIDS are at risk of fungal infections. These infections can be life-threatening, especially when they spread throughout the body. Nystatin is sometimes given as a routine preventive measure or as treatment in these patients. The review found that nystatin was no better than placebo (no ...
  9. 4 Sep 2014
    Prevention of fungal infections in patients with cancer with antifungal drugs Updated
    Cancer patients receiving chemotherapy or a bone marrow transplant are at risk of fungal infections. These can be life-threatening, especially when they spread throughout the body. Those patients with low white cell counts (neutropenia) are particularly at risk. Antifungal drugs are often given as a routine preventive measure, or when people who are ...
  10. 4 Sep 2014
    Treatment with or without anthracycline chemotherapy for childhood cancer Updated
    Anthracyclines are used in the treatment of different types of childhood cancer. Unfortunately, one of the most important adverse effects of anthracyclines is damage to the heart. This can become manifest not only during treatment but also years after the end of treatment. A well-informed decision on the use of anthracyclines in the treatment of different ...

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