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  1. 23 Dec 2014
    Does a local anaesthetic injection in children and young people having dental treatment under general anaesthetic reduce pain after treatment? New
    Review question Do injections of local anaesthetic given whilst children and young people (aged 17 years or younger) are having dental treatment under general anaesthetic reduce the amount of pain felt afterwards? Background It can be difficult when giving dental treatment to children and young people to do it simply using a local anaesthetic (LA) ...
  2. 11 Dec 2014
    Peripheral nerve blocks for postoperative pain after major knee surgery New
    There are different types of knee surgery which aim to treat joint stiffness or to reconstruct or repair the knee joint. Poorly controlled pain immediately after knee surgery is still a key issue. Pain-relieving medicines (analgesics) that are injected into the nerve are called peripheral nerve blocks. Nerve blocks are often used after major knee surgery, ...
  3. 26 Nov 2014
    Topical rubefacients for acute and chronic musculoskeletal pain in adults
    This is an update of a review of rubefacients for acute and chronic pain, originally published in 2009, that includes one new study. A topical medication is a one that is applied to body surfaces such as the skin to treat ailments. Topical products might be creams, foams, gels, lotions, and ointments. Topical products can include a large range of medicines. Rubefacients ...
  4. 16 Oct 2014
    Lidocaine for pain relief in people with burns
    Background Burns are very common and sometimes fatal, and the pain associated with such injury is one of the most difficult types to relieve. The use of high-dose opioid medications like morphine is common, but side effects are encountered. Alternative agents such as lidocaine, an anaesthetic, have been proposed. This is an update of the review of the ...
  5. 10 Oct 2014
    Intranasal fentanyl for the treatment of children in acute pain
    Background Pain is the most common reason why patients are seen in emergency departments (EDs). The challenging nature of treating children in acute severe pain is reflected in the medical literature by poor pain management in this population. We reviewed evidence on the effect of intranasal fentanyl (INF) (a strong pain relief drug, similar to morphine) ...
  6. 31 Jul 2014
    Does the administration of nalbuphine provide effective and safe postoperative pain treatment in children?
    Postoperative pain is still a major problem following surgery in children. There is currently clear evidence that multimodal postoperative pain treatment is the best choice. This approach may involve using nonsteroidal anti-inflammatory drugs (NSAIDs) and opioids. However, due to the fear of side effects such as respiratory depression (where the lungs ...
  7. 25 Jul 2014
    Botulinum toxin injectable drug for myofascial pain syndrome (a painful condition that could affect any muscle in the body) in adults
    Myofascial pain syndrome (MPS) is a regional muscular pain syndrome characterised by the presence of trigger points (painful points) in one or more muscles. The pain can be at the trigger point site or it can be felt away from that point when the muscle is pressed, which is called referred pain. Botulinum toxin is a potent chemical that blocks the communication ...
  8. 26 May 2014
    Psychological treatments to reduce pain in people undergoing open heart surgery
    Acute postoperative pain is one of the most disturbing complaints in open heart surgery, and is related to a risk of negative consequences such as impaired wound healing, chronic pain or depression. Psychological treatment is designed to improve patients' knowledge and to alter surgery-related mental distress, negative beliefs and non-compliance. It ...
  9. 13 May 2014
    Femoral nerve blocks for acute postoperative pain after knee replacement surgery
    Total knee replacement is a common and often painful orthopaedic operation. Femoral nerve block (FNB) is an analgesic technique that blocks sensation to the knee to reduce pain following surgery. FNB is given as a single injection or as continuous infusion of numbing medication in the groin area. This review compared FNB with other common analgesic ...
  10. 8 May 2014
    Single dose oral etoricoxib for acute postoperative pain in adults Podcast
    Acute pain is often felt soon after injury. Most people who have surgery have moderate or severe pain afterwards. People with pain are used to test painkillers. They have often had wisdom teeth removed. The pain is often treated with pain killers taken by mouth. Results can be applied to other forms of acute pain. A series of reviews looks at how good ...

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