Chemotherapy and radiotherapy bladder sparing treatment versus cystectomy for locally advanced bladder cancer

Worldwide, bladder cancer is common in both men and women. Local treatments such as surgery, radiation therapy (radiotherapy), or a combination of both can be used to try to treat advanced bladder cancer. Chemotherapy (anti-cancer drugs) can also be used. Chemotherapy drugs such as cisplatin are therefore sometimes given to people with advanced bladder ...

Bladder cancer is common worldwide. In rare cases, cancer spreads to the bladder muscle. A combination of surgery and radiation therapy (radiotherapy) is used to try to treat bladder cancer that has invaded the muscle. One treatment involves some radiotherapy, followed by major surgery to remove the bladder. Another treatment uses intensive radiotherapy, ...

Standard treatments for invasive bladder cancer are either surgery (to remove the bladder and surrounding tissues) or radiotherapy (to kill the cancer cells). This review suggested that 54 out of every 100 patients who had chemotherapy after surgery were alive after three years, compared to 45 out of every 100 patients who received only surgery. Although ...

The standard treatment for invasive bladder cancer is surgery (to remove the bladder and surrounding tissues), and/or radiotherapy (to kill the cancer cells). This review suggests that 50 out of 100 patients will be alive at five years, when they are given chemotherapy using a platinum drug in combination with other drugs, before having surgery and/or ...

When bladder cancer has spread beyond the bladder and is unresectable or metastatic, the possibility of cure is severely diminished. Treatment at this stage of the disease aims to reduce the disease-related symptoms and to improve quality of life. Chemotherapy is the main treatment offered to patients with this condition and one drug that has recently ...

Improved survival and local control rate have made the combination of external beam radiotherapy (EBRT) and intracavitary brachytherapy (ICBT) the standard treatment for locally advanced uterine cervix cancer. The use of high dose rate (HDR) brachytherapy is the result of technological developments. The evidence from our systematic review of clinical ...

In women with locally advanced vulval cancer (vulval cancer extending to urethra, vagina, perineum, anus, bladder, rectum, fixed to bones and enlarged fixed lymph glands) there was no significant difference in overall survival or treatment-related adverse events when primary chemoradiation or neoadjuvant chemoradiation (chemoradiation followed by less ...

Breathing oxygen while at raised pressure in a closed chamber (hyperbaric oxygen or HBO) may increase the effectiveness of Breathing HBO involves enclosing patients in a specially designed chamber and it is sometimes used to increase the effect of radiotherapy and thus improve both mortality and tumour regrowth. We found some evidence that people with ...