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  1. 21 Oct 2014
    Immunotherapy for recurrent miscarriage Updated
    Immunotherapy does not lower the risk of future miscarriage in women who repeatedly miscarry. Background Recurrent miscarriage is three or more consecutive early miscarriages. One theory is that for some women, this might be caused by an immune system response to the embryo or fetus. Therapies that try to immunize the woman against the 'foreign' cells ...
  2. 21 Oct 2014
    Interventions for managing asthma in pregnancy New
    Asthma is the most common disorder of the respiratory system (the organs that help you breathe) in pregnancy, affecting up to one in eight women. During pregnancy asthma can improve, worsen or remain unchanged. Poorly controlled asthma may lead to complications for mothers including pre-eclampsia (high blood pressure and protein in the urine), gestational ...
  3. 20 Oct 2014
    Prophylactic antibiotics for manual removal of retained placenta in vaginal birth Updated
    We did not identify any trials to say if women with retained placenta after giving birth would benefit from routine antibiotics prior to manual removal of placenta. Following the birth of her baby, a mother normally delivers the placenta with further pushing and support from her caregivers. Sometimes the placenta gets stuck on the wall of the womb (retained ...
  4. 13 Oct 2014
    Antibiotic prophylaxis for operative vaginal delivery Updated
    Background Vacuum and forceps assisted vaginal births are reported to increase the incidence of postpartum infections and maternal readmission to hospital compared to spontaneous vaginal birth. The commonest indications for operative vaginal delivery are prolonged second stage of labour, suspicion of immediate or potential fetal compromise and shortening ...
  5. 10 Oct 2014
    The effect of taking antimalarial drugs routinely to prevent malaria in pregnancy Updated
    Pregnancy increases the risk of malaria and this is associated with poor health outcomes for both the mother and the infant, especially during the first or second pregnancy. For this reason, women are encouraged to try and prevent malaria infection during pregnancy by sleeping under mosquito bed-nets, and by taking drugs effective against malaria throughout ...
  6. 9 Oct 2014
    High-dose versus low-dose oxytocin infusion regimens for induction of labour New
    Some women do not begin labour spontaneously and may need assistance. This assistance, known as induction of labour, involves the use of an intervention to artificially commence uterine contractions for the mother. Oxytocin is a drug that is commonly given to women for induction of labour; however the most suitable dose to enable birth to occur safely ...
  7. 8 Oct 2014
    Early versus late initiation of epidural analgesia for labour New
    Epidural analgesia involves the injection of medication just outside the spinal column. It is an effective form of pain relief during labour. The intensity of the pain increases as labour progresses. Epidural analgesia is an invasive procedure with side effects and more rarely complications. Reported side effects include muscle weakness, nausea, shivering, ...
  8. 7 Oct 2014
    Fetal pulse oximetry for fetal assessment in labour Updated
    Using fetal pulse oximetry to assess the baby's well-being during labour does not change overall caesarean section rates. During labour, the well-being of the baby can be assessed intermittently using a Pinard stethoscope or hand-held monitor to listen to the heart rate, or continuously using cardiotocography (CTG), sometimes called electronic fetal ...
  9. 7 Oct 2014
    Antibiotic prophylaxis for third- and fourth-degree perineal tear during vaginal birth Updated
    Background Most women are able to give birth without serious damage to their perineum. However, severe perineal trauma, which affects the muscle or tissue in the back passage, occurs in 1% to 8% of women giving birth and is common when forceps are used. There is an increased chance of infection when this happens. Pain in this area can impact not ...
  10. 3 Oct 2014
    Fetal assessment methods after preterm prelabour rupture of membranes for improving outcomes for mothers and babies New
    In a small number of pregnancies, the sac (membranes) surrounding the baby ruptures preterm, before 37 weeks of gestation, and before onset of labour. Preterm prelabour rupture of membranes (PPROM) occurs in around a third of all preterm births but the cause is often unknown. PPROM can result in illness and death for both the mother and baby through ...

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