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  1. 29 Oct 2014
    Antenatal screening tests for the prevention and treatment of syphilis New
    Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum. A major public health issue in developing countries, the condition develops over four stages and is potentially fatal if untreated. A pregnant woman with syphilis can transmit the infection to her baby, which may result in a severe condition in liveborn infants, ...
  2. 29 Oct 2014
    Antibiotics for rupture of membranes when a pregnant women is at or near term but not in labour Updated
    Background Sometimes the protective bag of fluid around an unborn baby (the membranes) break when the baby is due without the onset of labour (regular uterine contractions). This is called PROM or prelabour rupture of the membranes. When this happens there is a risk of infection entering the womb (uterus) and affecting the mother and her baby. Newborn ...
  3. 28 Oct 2014
    Spina bifida repair and infant and maternal health New
    Spina bifida is the term used to describe a group of neural tube conditions where the fetal spinal cord does not close properly during the first month of pregnancy. With open spina bifida some of the vertebrae are not completely formed but are split or divided and the spinal cord and its coverings (the meninges) protrude through the opening. The most ...
  4. 28 Oct 2014
    Routine antibiotics at cesarean section to reduce infection Updated
    Women undergoing cesarean section have a five to 20-fold greater chance of getting an infection compared with women who give birth vaginally. These infections can be in the organs within the pelvis, around the surgical incision and sometimes the urine. The infections can be serious, and very occasionally can lead to the mother’s death. The potential ...
  5. 21 Oct 2014
    Immunotherapy for recurrent miscarriage Updated
    Immunotherapy does not lower the risk of future miscarriage in women who repeatedly miscarry. Background Recurrent miscarriage is three or more consecutive early miscarriages. One theory is that for some women, this might be caused by an immune system response to the embryo or fetus. Therapies that try to immunize the woman against the 'foreign' cells ...
  6. 21 Oct 2014
    Interventions for managing asthma in pregnancy New
    Asthma is the most common disorder of the respiratory system (the organs that help you breathe) in pregnancy, affecting up to one in eight women. During pregnancy asthma can improve, worsen or remain unchanged. Poorly controlled asthma may lead to complications for mothers including pre-eclampsia (high blood pressure and protein in the urine), gestational ...
  7. 20 Oct 2014
    Prophylactic antibiotics for manual removal of retained placenta in vaginal birth Updated
    We did not identify any trials to say if women with retained placenta after giving birth would benefit from routine antibiotics prior to manual removal of placenta. Following the birth of her baby, a mother normally delivers the placenta with further pushing and support from her caregivers. Sometimes the placenta gets stuck on the wall of the womb (retained ...
  8. 13 Oct 2014
    Antibiotic prophylaxis for operative vaginal delivery Updated
    Background Vacuum and forceps assisted vaginal births are reported to increase the incidence of postpartum infections and maternal readmission to hospital compared to spontaneous vaginal birth. The commonest indications for operative vaginal delivery are prolonged second stage of labour, suspicion of immediate or potential fetal compromise and shortening ...
  9. 10 Oct 2014
    The effect of taking antimalarial drugs routinely to prevent malaria in pregnancy Updated
    Pregnancy increases the risk of malaria and this is associated with poor health outcomes for both the mother and the infant, especially during the first or second pregnancy. For this reason, women are encouraged to try and prevent malaria infection during pregnancy by sleeping under mosquito bed-nets, and by taking drugs effective against malaria throughout ...
  10. 9 Oct 2014
    High-dose versus low-dose oxytocin infusion regimens for induction of labour New
    Some women do not begin labour spontaneously and may need assistance. This assistance, known as induction of labour, involves the use of an intervention to artificially commence uterine contractions for the mother. Oxytocin is a drug that is commonly given to women for induction of labour; however the most suitable dose to enable birth to occur safely ...

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