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  1. 8 Aug 2014
    Surgery for obesity Podcast Updated
    Review question What are the effects of weight loss (bariatric) surgery for overweight or obese adults? Background Obesity is associated with many health problems and a higher risk of death. Bariatric surgery for obesity is usually only considered when other treatments have failed. We aimed to compare surgical interventions with non-surgical interventions ...
  2. 6 Aug 2014
    Drugs for treating urinary schistosomiasis Podcast Updated
    What is urinary schistosomiasis and how is it treated? Urinary schistosomiasis is a disease caused by infection of people with the parasitic worm Schistosoma haematobium. These worms live in blood vessels around the infected person's bladder and the worm releases eggs which are released in the person's urine. If the urine is passed into ponds or lakes, ...
  3. 29 Jul 2014
    Clot-dissolving drugs for treating ischaemic stroke in the early stages Podcast Updated
    Question We wanted to compare the safety and efficacy of clot-dissolving (thrombolytic) drugs versus placebo or no treatment in the early stages of ischaemic stroke to see if clot-dissolving drugs improve outcome after stroke. Background Most strokes are due to blockage of an artery in the brain by a blood clot. Prompt treatment with clot-dissolving ...
  4. 28 Jul 2014
    Hysterectomy versus hysterectomy plus ovary removal for premenopausal women Podcast
    Review question: Cochrane authors reviewed the evidence on the risks and benefits of the removal or conservation of ovaries at the time of hysterectomy for benign gynaecological disease in premenopausal women. Background: removing the ovaries at the time of hysterectomy could potentially reduce the risk of ovarian cancer and the need for future gynaecological ...
  5. 27 Jun 2014
    Heparins reduce the number of heart attacks but caused more minor bleeding after non-ST elevation acute coronary syndromes compared with placebo Podcast
    Blood clots in the arteries leading to the heart can cause acute coronary syndromes: unstable angina (a feeling of tightness in the chest) or a type of heart attack (non-ST segment myocardial infarction - NSTEMI). Drugs that prevent clots from forming (such as aspirin) or thin the blood (such as heparin) can relieve the problem. Unfractionated heparin ...
  6. 12 Jun 2014
    Efficacy and safety of trastuzumab in metastatic breast cancer Podcast
    Tumours characterised by the presence of the HER2 protein are found in about one in five women with metastatic breast cancer. These tend to be more aggressive and the prognosis and choice of treatment are affected. Trastuzumab (Herceptin®) is a targeted biological drug (a monoclonal antibody) that attaches to the HER2 protein, blocking the growth of ...
  7. 8 May 2014
    Single dose oral etoricoxib for acute postoperative pain in adults Podcast
    Acute pain is often felt soon after injury. Most people who have surgery have moderate or severe pain afterwards. People with pain are used to test painkillers. They have often had wisdom teeth removed. The pain is often treated with pain killers taken by mouth. Results can be applied to other forms of acute pain. A series of reviews looks at how good ...
  8. 29 Apr 2014
    Strategies to improve safe and effective medicines use by consumers: an overview of systematic reviews Podcast
    Review question: This is an update of an overview first published in 2011. Researchers in the Cochrane Collaboration reviewed the evidence from systematic reviews about the effects of interventions to improve safe and effective medicines use by consumers, irrespective of disease, medicine type, population or setting. Background: Medicines are a cornerstone ...
  9. 29 Apr 2014
    Stem cell treatment for chronic ischaemic heart disease and congestive heart failure Podcast
    Those suffering from heart disease and heart failure are currently treated with drugs and, when possible, the blood supply is restored in the heart (revascularisation) either by opening the arteries with a tiny balloon in a procedure called primary angioplasty (or percutaneous coronary intervention (PCI)) or by heart surgery (or coronary artery bypass ...
  10. 22 Apr 2014
    Physical rehabilitation approaches for recovery of function, balance and walking after stroke Podcast
    Question We wanted to know whether physical rehabilitation approaches are effective in recovery of function and mobility in people with stroke, and if any one physical rehabilitation approach is more effective than any other approach. Background Stroke can cause paralysis of some parts of the body and other difficulties with various physical functions. ...

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