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  1. 27 Jun 2014
    Heparins reduce the number of heart attacks but caused more minor bleeding after non-ST elevation acute coronary syndromes compared with placebo Podcast Updated
    Blood clots in the arteries leading to the heart can cause acute coronary syndromes: unstable angina (a feeling of tightness in the chest) or a type of heart attack (non-ST segment myocardial infarction - NSTEMI). Drugs that prevent clots from forming (such as aspirin) or thin the blood (such as heparin) can relieve the problem. Unfractionated heparin ...
  2. 12 Jun 2014
    Efficacy and safety of trastuzumab in metastatic breast cancer Podcast New
    Tumours characterised by the presence of the HER2 protein are found in about one in five women with metastatic breast cancer. These tend to be more aggressive and the prognosis and choice of treatment are affected. Trastuzumab (Herceptin®) is a targeted biological drug (a monoclonal antibody) that attaches to the HER2 protein, blocking the growth of ...
  3. 8 May 2014
    Single dose oral etoricoxib for acute postoperative pain in adults Podcast
    Acute pain is often felt soon after injury. Most people who have surgery have moderate or severe pain afterwards. People with pain are used to test painkillers. They have often had wisdom teeth removed. The pain is often treated with pain killers taken by mouth. Results can be applied to other forms of acute pain. A series of reviews looks at how good ...
  4. 29 Apr 2014
    Stem cell treatment for chronic ischaemic heart disease and congestive heart failure Podcast
    Those suffering from heart disease and heart failure are currently treated with drugs and, when possible, the blood supply is restored in the heart (revascularisation) either by opening the arteries with a tiny balloon in a procedure called primary angioplasty (or percutaneous coronary intervention (PCI)) or by heart surgery (or coronary artery bypass ...
  5. 29 Apr 2014
    Strategies to improve safe and effective medicines use by consumers: an overview of systematic reviews Podcast
    Review question: This is an update of an overview first published in 2011. Researchers in the Cochrane Collaboration reviewed the evidence from systematic reviews about the effects of interventions to improve safe and effective medicines use by consumers, irrespective of disease, medicine type, population or setting. Background: Medicines are a cornerstone ...
  6. 22 Apr 2014
    Physical rehabilitation approaches for recovery of function, balance and walking after stroke Podcast
    Question We wanted to know whether physical rehabilitation approaches are effective in recovery of function and mobility in people with stroke, and if any one physical rehabilitation approach is more effective than any other approach. Background Stroke can cause paralysis of some parts of the body and other difficulties with various physical functions. ...
  7. 11 Apr 2014
    Stimulating the brain without surgery in the management of chronic pain Podcast
    Various devices are available that can electrically stimulate the brain without the need for surgery or any invasive treatment in order to manage chronic pain. There are four main treatment types: repetitive transcranial magnetic stimulation (rTMS) in which the brain is stimulated by a coil applied to the scalp, cranial electrotherapy stimulation (CES) ...
  8. 31 Mar 2014
    Hip protectors for preventing hip fractures in older people Podcast
    What are hip protectors? Older people living in nursing care facilities or older adults living at home are at high risk of falling and a hip fracture may occur after a fall. Hip protectors are plastic shields (hard) or foam pads (soft), usually fitted in pockets in specially designed underwear. They are worn to cushion a sideways fall on the hip. Do ...
  9. 30 Mar 2014
    Selenium for preventing cancer Podcast
    Review question We reviewed the evidence suggesting that selenium can help to prevent cancer. This review updates the first Cochrane review on this topic (Dennert 2011). Background Selenium is a naturally occurring element found in crops, animal products and water. Small amounts of selenium are needed for proper human nutrition. Starting in the ...
  10. 14 Mar 2014
    Rehabilitation after surgery for herniation of the lumbar disc Podcast
    Review question We reviewed the evidence on the effects of rehabilitation programmes on pain, recovery, function and return to work in people who have had lumbar disc surgery. Background A 'slipped' or 'herniated' disc is thought to be the most common cause of leg pain associated with a 'pinched' or compressed nerve in the lower back. Many patients ...

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