PEARLS

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  1. 29 Aug 2014
    Do exercise interventions help people quit smoking Podcast Updated
    Review question We reviewed the evidence about the effect of exercise programmes in people who want to quit smoking. We looked at whether exercise programmes, either alone or combined with stop smoking programmes, helped more people to quit at six months or longer than stop smoking programmes alone or stop smoking programmes combined with health education. Background Specialist ...
  2. 26 Aug 2014
    Methotrexate for treatment of inactive Crohn's disease Updated
    Crohn's disease is a chronic inflammatory disease of the intestines that frequently occurs in the lower part of the small intestine, called the ileum. However, Crohn’s disease can affect any part of the digestive tract, from the mouth to the anus. The most common symptoms are abdominal pain and diarrhea. Prevention of clinical relapse (resumption of ...
  3. 15 Aug 2014
    Colchicine for treating acute gout attacks Updated
    We reviewed the evidence about the benefits and harms of colchicine in acute gout up to April 2014 and identified two trials. One trial included 43 participants and compared high-dose colchicine (1 mg of colchicine followed by 0.5 mg every two hours until the attack resolved or participants had side effects (total dose unspecified)) to placebo. The ...
  4. 8 Aug 2014
    Surgery for obesity Podcast Updated
    Review question What are the effects of weight loss (bariatric) surgery for overweight or obese adults? Background Obesity is associated with many health problems and a higher risk of death. Bariatric surgery for obesity is usually only considered when other treatments have failed. We aimed to compare surgical interventions with non-surgical interventions ...
  5. 23 Jul 2014
    Treatment of amblyopia (lazy eye) caused by strabismus (squint) with patching or optical treatment (glasses or penalisation) or both
    Review question: Treatment of amblyopia (lazy eye) caused by strabismus (squint) with patching or optical treatment (glasses or penalisation) or both. Background: Amblyopia is a common childhood condition which causes a reduction in vision of one or both eyes which is not caused by any eye disease. Amblyopia can be caused by the presence of a squint ...
  6. 8 Jul 2014
    Blood thinners for the long-term treatment of blood clots in patients with cancer
    Background Patients with cancer are at an increased risk of developing blood clots and might respond differently to blood thinners (anticoagulants) compared with patients without cancer. Study characteristics We searched scientific databases for clinical trials looking at the effects of long-term treatment with different blood thinners on blood ...
  7. 7 Jul 2014
    Interventions to increase influenza (flu) vaccination uptake for people aged 60 and older
    Many health authorities recommend influenza vaccination of older people. However, vaccination uptake in people aged 60 and older varies across countries, socioeconomic and health-risk groups. It is important to identify effective interventions to increase influenza vaccination uptake. We included 57 randomised controlled trials (RCTs) with 896,531 participants ...
  8. 29 Jun 2014
    Zinc supplements for preventing middle ear infections
    Background Middle ear infections are common, especially among young children, usually causing earache and some temporary (occasionally permanent) hearing loss. Zinc is an essential micronutrient, which has a role in the optimal functioning of the immune system and resistance to infection. It must be consumed regularly as it cannot be stored in the ...
  9. 27 Jun 2014
    Heparins reduce the number of heart attacks but caused more minor bleeding after non-ST elevation acute coronary syndromes compared with placebo Podcast
    Blood clots in the arteries leading to the heart can cause acute coronary syndromes: unstable angina (a feeling of tightness in the chest) or a type of heart attack (non-ST segment myocardial infarction - NSTEMI). Drugs that prevent clots from forming (such as aspirin) or thin the blood (such as heparin) can relieve the problem. Unfractionated heparin ...
  10. 25 Jun 2014
    Promoting patient uptake and adherence in cardiac rehabilitation
    Background Cardiac rehabilitation programs aid recovery from cardiac events such as heart attacks, coronary stent placement, and bypass surgery and reduce the likelihood of further illness. Cardiac rehabilitation programs vary, but usually include one or more of the following: exercise, education, and psychological counselling/support. Despite the ...

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