PEARLS

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  1. 28 Oct 2014
    Routine antibiotics at cesarean section to reduce infection Updated
    Women undergoing cesarean section have a five to 20-fold greater chance of getting an infection compared with women who give birth vaginally. These infections can be in the organs within the pelvis, around the surgical incision and sometimes the urine. The infections can be serious, and very occasionally can lead to the mother’s death. The potential ...
  2. 17 Sep 2014
    Opioids for osteoarthritis Updated
    This summary of a Cochrane review of 22 studies with 8275 participants (search update: 15 August 2012) presents what we know from research about the effect of opioids on osteoarthritis (OA). We searched scientific databases for clinical trials looking at pain, function, safety, and addiction of oral or transdermal opioids compared with placebo or no ...
  3. 15 Sep 2014
    Rapid viral testing for children in the Emergency Department with fever and respiratory symptoms Updated
    Review question Does rapid viral testing in the Emergency Department influence the treatment of children with fever and breathing symptoms? Background Otherwise healthy children, aged 0 to 18 years, admitted to Emergency Departments (EDs) with fever and respiratory symptoms represent a major burden to the healthcare system, as well as significant ...
  4. 9 Sep 2014
    Vaginal cleansing before cesarean delivery to reduce post-cesarean infections Updated
    Cesarean deliveries are very common today, with almost one in three babies born by cesarean in some countries. Antibiotics are routinely given before or during the surgery to reduce the risk of infections, but some women still suffer from these complications. Between one in four and one in 10 women develop an infection of the uterus (endometritis) or ...
  5. 4 Sep 2014
    Culturally appropriate health education for people in ethnic minority groups with type 2 diabetes mellitus Updated
    Review question Does culturally appropriate diabetes health education lead to better outcomes than 'usual care' for people in ethnic minority groups with type 2 diabetes? Background In upper-middle-income and high-income countries, minority ethnic groups often have a higher prevalence of type 2 diabetes mellitus than is seen in the local population. ...
  6. 1 Sep 2014
    Statins for acute coronary syndrome Podcast Updated
    Long-term therapy with statins (for at least one year) has been shown to reduce the risk of heart attack, stroke, and all-cause mortality in patients with and without established coronary heart disease. The early period following an acute coronary syndrome is a critical stage of coronary heart disease, with a high risk of recurrent events and death. ...
  7. 29 Aug 2014
    Do exercise interventions help people quit smoking Podcast
    Review question We reviewed the evidence about the effect of exercise programmes in people who want to quit smoking. We looked at whether exercise programmes, either alone or combined with stop smoking programmes, helped more people to quit at six months or longer than stop smoking programmes alone or stop smoking programmes combined with health education. Background Specialist ...
  8. 26 Aug 2014
    Methotrexate for treatment of inactive Crohn's disease
    Crohn's disease is a chronic inflammatory disease of the intestines that frequently occurs in the lower part of the small intestine, called the ileum. However, Crohn’s disease can affect any part of the digestive tract, from the mouth to the anus. The most common symptoms are abdominal pain and diarrhea. Prevention of clinical relapse (resumption of ...
  9. 15 Aug 2014
    Colchicine for treating acute gout attacks
    We reviewed the evidence about the benefits and harms of colchicine in acute gout up to April 2014 and identified two trials. One trial included 43 participants and compared high-dose colchicine (1 mg of colchicine followed by 0.5 mg every two hours until the attack resolved or participants had side effects (total dose unspecified)) to placebo. The ...
  10. 8 Aug 2014
    Surgery for obesity
    Review question What are the effects of weight loss (bariatric) surgery for overweight or obese adults? Background Obesity is associated with many health problems and a higher risk of death. Bariatric surgery for obesity is usually only considered when other treatments have failed. We aimed to compare surgical interventions with non-surgical interventions ...

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