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  1. 25 Oct 2014
    Probiotics for preventing ventilator-associated pneumonia New
    Review question To critically assess the current evidence from published studies relating to the effect of probiotics for preventing ventilator-associated pneumonia (VAP). Background VAP is a condition that can occur in patients who have been mechanically ventilated for more than 48 hours and can significantly increase the likelihood of death within ...
  2. 24 Oct 2014
    Antiangiogenic therapy for diabetic macular oedema Updated
    Background Diabetic macular oedema (DMO) is a common complication of diabetic retinopathy. The retina at the macula thickens and this can cause gradual loss of central vision. Grid or focal laser photocoagulation is effective in treating DMO and has been used for several years, but vision is rarely improved. Review question We have reviewed the ...
  3. 24 Oct 2014
    Treatments to cure long-term infections with Burkholderia cepacia in people with cystic fibrosis New
    Review question We reviewed the evidence for antibiotic treatment to cure early infection with Burkholderia cepacia complex in people with cystic fibrosis and prevent it becoming permanent. Background Cystic fibrosis is an inherited disease and people who have this disease produce large amounts of thick mucus which is difficult to clear. This mucus ...
  4. 24 Oct 2014
    Do school tobacco policies prevent uptake of smoking? New
    Background: We reviewed the evidence that School tobacco policies (STPs) might prevent smoking initiation among adolescents, as there may be some evidence that the school environment can influence young people to smoke. STP is intended to regulate whether and where pupils can smoke, adult smoking in school, and penalties for pupils caught smoking. ...
  5. 23 Oct 2014
    Pharmacotherapy for tooth grinding or clenching during the sleep (sleep bruxism) New
    Background There are several signs and symptoms of sleep bruxism, such as abnormal tooth wear, fractured teeth, jaw muscle discomfort, joint pain or tenderness, and headaches. Treatments include odontological devices such as occlusal splints, psychotherapy and medications (pharmacotherapy). Pharmacological treatments include drugs such as benzodiazepines, ...
  6. 23 Oct 2014
    Tolerability of selective cyclooxygenase 2 (COX-2) inhibitors used for the treatment of rheumatological manifestations of inflammatory bowel disease New
    Nonsteroidal anti-inflammatory drugs (NSAIDs) are used to reduce inflammatory pain and swelling in inflammatory bowel disease (IBD) patients with rheumatological manifestations (e.g. arthritis). While these drugs effectively reduce musculoskeletal pain and stiffness, long-term use is limited by gastrointestinal (GI) side effects and disease exacerbation ...
  7. 22 Oct 2014
    Astragalus (a traditional Chinese medicine) for treating chronic kidney disease New
    Chronic kidney disease affects increasing numbers of people around the world, but as yet, effective strategies to control its progression have not been universally accepted. Astragalus is one of most widely used herbs for treating kidney disease. We conducted this review to evaluate the benefits and potential harms of Astragalus for the treatment of ...
  8. 21 Oct 2014
    Immunotherapy for recurrent miscarriage Updated
    Immunotherapy does not lower the risk of future miscarriage in women who repeatedly miscarry. Background Recurrent miscarriage is three or more consecutive early miscarriages. One theory is that for some women, this might be caused by an immune system response to the embryo or fetus. Therapies that try to immunize the woman against the 'foreign' cells ...
  9. 21 Oct 2014
    Minimally invasive surgical techniques versus open myomectomy for uterine fibroids New
    Review question: In this Cochrane review, we compared surgical results after myomectomy by open surgery versus myomectomy by laparoscopy and hysteroscopy. Background: Fibroids are common benign tumours arising in the uterus. Sometimes they cause problems such as abnormal vaginal bleeding, pain and difficulty passing urine and bowel motions. Fibroids ...
  10. 21 Oct 2014
    Interventions for managing asthma in pregnancy New
    Asthma is the most common disorder of the respiratory system (the organs that help you breathe) in pregnancy, affecting up to one in eight women. During pregnancy asthma can improve, worsen or remain unchanged. Poorly controlled asthma may lead to complications for mothers including pre-eclampsia (high blood pressure and protein in the urine), gestational ...

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