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  1. 27 Aug 2014
    Haemodilution for acute ischaemic stroke Updated
    Question We wanted to compare the effectiveness of haemodilution (diluting the blood) treatment, started within 72 hours of stroke onset, versus control or no treatment in people with ischaemic stroke to assess the impact on death or dependence. Background Stroke is the second leading cause of death worldwide. Symptoms of stroke include face drooping, ...
  2. 27 Aug 2014
    Methotrexate for treatment of chronic active ulcerative colitis Updated
    Ulcerative colitis is a chronic inflammatory bowel disease characterized by abdominal cramping, fecal urgency and bloody diarrhea. Methotrexate is a drug that suppresses the body's natural immune responses and may suppress inflammation associated with ulcerative colitis. The purpose of this systematic review was to examine the effectiveness and side ...
  3. 26 Aug 2014
    Methotrexate for treatment of inactive Crohn's disease Updated
    Crohn's disease is a chronic inflammatory disease of the intestines that frequently occurs in the lower part of the small intestine, called the ileum. However, Crohn’s disease can affect any part of the digestive tract, from the mouth to the anus. The most common symptoms are abdominal pain and diarrhea. Prevention of clinical relapse (resumption of ...
  4. 26 Aug 2014
    Interventions to prevent embryos from being expelled after transfer in women undergoing in vitro fertilisation and intracytoplasmic sperm injection Updated
    Review question In women undergoing in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI) what are the best methods to prevent embryos from being expelled after the embryo transfer (ET) procedure? Background In recent years assisted reproduction has become more evidence based in an attempt to determine what techniques truly work. ...
  5. 26 Aug 2014
    Manual therapy and exercise for frozen shoulder (adhesive capsulitis) New
    Background Frozen shoulder is a common cause of shoulder pain and stiffness. The pain and stiffness can last up to two to three years before going away, and in the early stages it can be very painful. Manual therapy comprises movement of the joints and other structures by a healthcare professional (e.g. physiotherapist). Exercise includes any purposeful ...
  6. 24 Aug 2014
    Monitoring of stimulated cycles in fertility treatment involving in vitro fertilisation (IVF) and intra-cytoplasmic sperm injection (ICSI) Updated
    Review question: can ultrasound alone be used safely without adding estradiol blood test measurements to monitor women undergoing controlled ovarian hyperstimulation during IVF and ICSI? We reviewed the evidence on monitoring women undergoing controlled ovarian hyperstimulation as part of IVF or ICSI by transvaginal ultrasound (TVUS) only versus traditional ...
  7. 22 Aug 2014
    Advanced training in trauma life support for hospital staff Updated
    Training in 'advanced trauma life support' (ATLS) is increasingly used in both rich and poor countries. ATLS is intended to improve the way in which care is given to injured people, thereby reducing death and disability. Some research has been done that suggests ATLS programmes improve the knowledge of staff who have been trained, but there have been ...
  8. 22 Aug 2014
    Angiotensin converting enzyme (ACE) inhibitors versus angiotensin receptor blockers for primary hypertension New
    Background Hypertension, or persistent high blood pressure above 140/90 mmHg, is a prevalent risk factor that is associated with strokes and heart disease. To prevent these events, angiotensin converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) are used widely to treat hypertension, with ARBs often substituted for ACE inhibitors ...
  9. 21 Aug 2014
    Advanced training in trauma life support for ambulance crews Updated
    Injury is one of the top ten causes of death and disability worldwide. It results in an early loss of life for many young people and ongoing high medical care costs among survivors. Advanced life support (ALS) training for ambulance crews with emphasis on trauma is believed to have contributed to a reduction in the number of deaths from injury in predominantly ...
  10. 21 Aug 2014
    Antioxidants to reduce pain in chronic pancreatitis New
    Chronic pancreatitis is a persistent inflammation of the pancreas that in the long run can cause irreparable damage. The major causes of chronic pancreatitis are genetics, alcohol toxicity and other conditions that might damage or obstruct the pancreas. This inflammation can cause pain that often is severe and leaves patients socially isolated and unable ...

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