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  1. 20 Oct 2014
    Prophylactic antibiotics for manual removal of retained placenta in vaginal birth Updated
    We did not identify any trials to say if women with retained placenta after giving birth would benefit from routine antibiotics prior to manual removal of placenta. Following the birth of her baby, a mother normally delivers the placenta with further pushing and support from her caregivers. Sometimes the placenta gets stuck on the wall of the womb (retained ...
  2. 19 Oct 2014
    Non-drug management of breathing problems for children with severe physical and intellectual impairment New
    Background For a variety of reasons, some children live with very severe intellectual and physical problems; they are unable to walk or talk and require a lot of care. In this study we refer to them as children with severe global developmental delay (SGDD); this is not a specific diagnosis but is rather an 'umbrella term' used to describe a group of ...
  3. 16 Oct 2014
    Immunosuppressive treatment for idiopathic membranous nephropathy in adults with nephrotic syndrome Updated
    Idiopathic membranous nephropathy (IMN) is a disease in which glomerular basement membrane becomes thickening by light microscopy on renal biopsy and it represents a major cause of primary nephrotic syndrome in adults. A combined alkylating agent and corticosteroid regimen had short- and long-term benefits on adult IMN with nephrotic syndrome. Among ...
  4. 16 Oct 2014
    The effect of pricing policies for pharmaceuticals Updated
    Researchers in The Cochrane Collaboration conducted a review of the effect of reference pricing and other pricing policies for pharmaceuticals. In 2012, they searched for all relevant studies and finally included 18 studies. Their findings are summarised below. What are reference pricing and other pricing policies for pharmaceuticals? Large amounts ...
  5. 16 Oct 2014
    Corticosteroid eye drops used in addition to standard antibiotic therapy in the treatment of bacterial keratitis Updated
    Review question We reviewed the available information regarding the added effect of corticosteroid eye drops in people with bacterial keratitis (corneal ulcers) who were also being treated with antibiotics. Background Bacterial keratitis, or corneal inflammation due to bacterial infection, is a sight-threatening condition. Contact lens wear, ocular ...
  6. 16 Oct 2014
    Lidocaine for pain relief in people with burns
    Background Burns are very common and sometimes fatal, and the pain associated with such injury is one of the most difficult types to relieve. The use of high-dose opioid medications like morphine is common, but side effects are encountered. Alternative agents such as lidocaine, an anaesthetic, have been proposed. This is an update of the review of the ...
  7. 15 Oct 2014
    Transplantation of blood-forming stem cells for people with ß-thalassaemia major Updated
    Thalassaemia is a blood disorder passed down through families (inherited) in which the body makes an abnormal form of haemoglobin (the protein in red blood cells that carries oxygen). The disorder results in excessive destruction of red blood cells, which, without blood transfusions, leads to anaemia and causes significant mortality and morbidity. The ...
  8. 15 Oct 2014
    Is it better to do strabismus (squint) surgery before or after completing amblyopia (lazy eye) treatment? New
    Background In normal development of vision, children are able to use the visual information from each of their two eyes to form a single image. When an infant or child's eyes are not properly aligned, this is called strabismus (also known as squint). With misalignment, the two eyes do not work together to relay visual information. The brain may suppress ...
  9. 15 Oct 2014
    Blood thinners to prevent blood clots in people with cancer and central venous catheters Updated
    Background A central venous catheter (CVC) is a tube that is inserted into a large vein to give fluids or drugs. CVC placement increases the risk of blood clots in people with cancer. This systematic review evaluated the efficacy and safety of blood thinning agents (anticoagulants) in people with cancer. Study characteristics We searched the scientific ...
  10. 15 Oct 2014
    Beta-blockers for preventing stroke recurrence Updated
    People who have had a stroke or a transient ischaemic attack (TIA) are at risk of having further strokes or heart attacks, or other serious circulatory problems. Beta-blockers are drugs that reduce heart rate and blood pressure, and have other effects that might also reduce the risks of stroke and heart attack. Searching for studies up to May 2014, ...

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