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The effects of high perioperative inspiratory oxygen fraction for adult surgical patients

Wetterslev J, Meyhoff CS, Jørgensen LN, Gluud C, Rasmussen LS
Published Online: 
December 8, 2010
This is the protocol for a review and there is no abstract. The objectives are as follows:

We will assess the benefits and harms of an FIO2 equal to or higher than 60% compared with a control FIO2 of 40% or below in the perioperative setting.

We will look at various outcomes, conduct subgroup and sensitivity analyses, examine the role of bias and apply trial sequential analyses (TSA) (Brok 2008; Brok 2009; Thorlund 2009; Wetterslev 2008) to examine the level of evidence for this intervention.

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