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Injectable local anaesthetic agents for operative dental anaesthesia

St George G, Hussain S, Meechan J, Moles DR, Needleman I
Published Online: 
January 21, 2009
This is the protocol for a review and there is no abstract. The objectives are as follows:

To determine what is the most effective local anaesthetic formulation for operative dental anaesthesia.

Our primary objective is to test

  • the adequacy of anaesthesia in patients when using different local anaesthetic formulations for operative dental anaesthesia;
  • the speed of onset and duration of anaesthesia in patients when using different local anaesthetic formulations for operative dental anaesthesia;
  • systemic and local adverse effects associated with dental local anaesthetic.

We define adequacy of anaesthesia as the absence of pain during a dental procedure, or a negative response to electric pulp testing.

We define operative dental anaesthesia as anaesthesia at the time of an operative intervention.

Our secondary objective is to report on

  • patients' experience of the procedures carried out;
  • the influence of modifying factors on efficacy of local anaesthetic formulations.
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