Colonoscopy is a diagnostic test that enables small growths in the bowel (polyps) to be detected. These lesions can develop into cancer in approximately 5% of the cases. Although the test is the most sensitive test that exists for the detection of these growths, some may be missed. If a simple dye spraying technique (chromoscopy) is used with the colonoscopic test, the detection of these lesions may be enhanced. Several studies have examined the effect of chromoscopy on enhancing polyp detection but the data is inconsistent. This review investigated whether chromoscopy can enhance polyp detection compared with conventional colonoscopy.
Five randomised trials with a total of 1059 participants were included. Despite differences within the study designs there appears to be strong evidence that chromoscopic colonoscopy enhances the detection of polyps in the colon and rectum.