Umckaloabo is a herbal extract derived from the plant Pelargonium sidoides (P. sidoides) and is available in both tablet and liquid forms. The extract is used for the treatment of acute respiratory tract infections (ARIs) where antibiotic use is unnecessary. In the light of inappropriate antibiotic use and increasing drug resistance rates worldwide, the need for an alternative, effective remedy for these medical conditions is crucial.
We reviewed eight randomized clinical trials with acceptable methodologies. Two trials showed that P. sidoides was effective in relieving all symptoms, and in particular cough and sputum production in adults with acute bronchitis. However, a third study showed that the preparation was only effective for treating sputum reduction. Similarly, P. sidoides was effective in resolving symptoms of acute bronchitis in two out of three pediatric studies. In acute sinusitis and the common cold P. sidoides was effective in resolving all symptoms including headaches and nasal discharge in adults when taken for an extended time period. Adverse events were more common with P. sidoides, but none were severe .
There is limited evidence for the effectiveness of P. sidoides in the treatment of ARIs. The herbal preparation may be effective in relieving symptoms in acute bronchitis in adults and children, and sinusitis in adults.