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Haloperidol for the treatment of nausea and vomiting in palliative care patients

Perkins P, Dorman S
Published Online: 
20 January 2010

We did not identify any randomised controlled trials (RCTs) to find out if haloperidol is a useful drug for the treatment of nausea or vomiting in palliative care patients. Nausea and vomiting are common problems for patients with serious life threatening illnesses and haloperidol is a drug which is sometimes prescribed to help treat these symptoms. This drug can be given orally or by injection. There has been some research looking at how this drug works in sickness caused by surgery and when trying to prevent sickness caused by anti-cancer treatments. During a search of the international literature no studies looking at this treatment in seriously ill or terminally ill patients were found. There is not enough evidence to be able to recommend haloperidol for the treatment of nausea and vomiting in adult patients suffering from incurable progressive medical conditions.