Cochrane Summaries

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There is some evidence from RCTs that antipsychotics are effective, in varying doses, for different presentations of delirium

Lonergan E, Britton AM, Luxenberg J
Published Online: 
21 January 2009

Haloperidol (<3.5 mg/d), risperidone, and olanzapine were equally effective in treating delirium, with few adverse effects. Parkinsonian adverse effects were common with higher dose haloperidol (>4.5 mg/d) compared with olanzapine. Pre-operative haloperidol decreased severity and duration of post-surgery delirium. All studies were small and should be repeated.

This record should be cited as: 
Lonergan E, Britton AM, Luxenberg J. Antipsychotics for delirium. Cochrane Database of Systematic Reviews 2007, Issue 2. Art. No.: CD005594. DOI: 10.1002/14651858.CD005594.pub2
Assessed as up to date: 
2 February 2007
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