We will determine the mortality and morbidity benefits of maintaining normoglycaemia using insulin therapy versus hyperglycaemia in all adult intensive care patients.
We will test the following primary null hypothesis:
The incidence of in hospital mortality is not altered by use of intensive insulin therapy versus conventional therapy.
We will test the following secondary hypotheses:
The incidence of nosocomial infection is not altered by use of intensive insulin therapy versus conventional therapy.
The incidence of days of mechanical ventilation is not altered by use of intensive insulin therapy versus conventional therapy.
The incidence of critical illness polyneuropathy is not altered by use of intensive insulin therapy versus conventional therapy.