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Risperidone for autism spectrum disorder

Jesner OS, Aref-Adib M, Coren E
Published Online: 
20 January 2010

Risperidone is an antipsychotic medication that has been used for symptom relief and behavioural improvement in autism. This review encompasses three randomised controlled trials and concludes that risperidone may be beneficial for various aspects of autism including irritability, repetition and hyperactivity. However, all studies were relatively small and used different ways to assess effectiveness, making comparisons difficult. In addition, side effects were identified, notably weight gain. Further studies are therefore necessary to determine the long term benefits, if any, compared with the potential risks.

This record should be cited as: 
Jesner OS, Aref-Adib M, Coren E. Risperidone for autism spectrum disorder. Cochrane Database of Systematic Reviews 2007, Issue 1. Art. No.: CD005040. DOI: 10.1002/14651858.CD005040.pub2
Assessed as up to date: 
4 April 2006