People with advanced kidney disease may be treated with peritoneal dialysis where a catheter is permanently inserted into the peritoneum (lining around abdominal contents) through the abdominal wall and sterile fluid is drained in and out a few times each day. The most common serious complication is infection of the peritoneum - peritonitis. This may be caused by bacteria accidentally being transferred from the catheter. This review found that nasal mupirocin reduces exit-site/tunnel infection but not peritonitis while preoperative intravenous antibiotic prophylaxis reduces early peritonitis but not exit-site/tunnel infection. More large scale trials are needed.
The nasal antibiotic prophylactic mupirocin reduces exit-site/tunnel infection and preoperative intravenous antibiotic prophylaxis reduces early peritonitis in peritoneal dialysis
14 April 2010
This record should be cited as:
Strippoli GFM, Tong A, Johnson DW, Schena FP, Craig JC. Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients. Cochrane Database of Systematic Reviews 2004, Issue 4. Art. No.: CD004679. DOI: 10.1002/14651858.CD004679.pub2
Assessed as up to date:
18 December 2007
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