Cochrane Summaries

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Single dose oral etoricoxib for acute pain relief in adults experiencing moderate or severe pain following a surgical procedure

Clarke R, Derry S, Moore R
Published Online: 
9 October 2013

Etoricoxib is a non-steroidal anti-inflammatory drug (NSAID) which produces relief of pain in a number of different painful conditions. This review looked at how good etoricoxib was in relieving moderate or severe pain following surgery. Six studies provided information. Etoricoxib 120 mg provided effective pain relief for almost 7 in 10 (66%) of participants, compared with just over 1 in 10 (12%) of participants with placebo. The duration of pain relief was much longer with etoricoxib, at over 20 hours, compared with two hours with placebo, making it one of the most effective oral analgesics in acute pain. Adverse events occurred at similar rates with etoricoxib and placebo. No serious adverse events or withdrawals due to adverse events occurred with etoricoxib.