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Antifungal drugs used for prevention can significantly reduce the number of invasive fungal infections in liver transplant patients

Playford EG, Webster AC, Craig JC, Sorrell TC
Published Online: 
8 July 2009

Invasive fungal infections - infections of the bloodstream and organs within the body (e.g. meningitis, pneumonia, peritonitis) - are important causes of morbidity and mortality in liver, pancreas, heart, kidney and lung (i.e. solid organ) transplant recipients. This review found that fluconazole, used as a preventive drug, significantly reduced the number of invasive fungal infections in liver transplant patients. More studies are needed to determine how effective antifungal drugs are for pancreas, heart, kidney and lung transplant patients.

This record should be cited as: 
Playford EG, Webster AC, Craig JC, Sorrell TC. Antifungal agents for preventing fungal infections in solid organ transplant recipients. Cochrane Database of Systematic Reviews 2004, Issue 3. Art. No.: CD004291. DOI: 10.1002/14651858.CD004291.pub2
Assessed as up to date: 
22 November 2005