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Vitamin C supplementation in pregnancy

Rumbold A, Crowther CA
Published Online: 
7 July 2010

Not enough evidence to determine if giving women vitamin C during pregnancy helps prevent babies dying, being born too soon or being born small.

Having a low intake of vitamin C may be associated with complications in pregnancy such as pre-eclampsia, anaemia and having a small baby. The review of trials found that there is not enough good evidence to say if supplementing women with vitamin C during pregnancy prevented the baby dying or being born small. Vitamin C supplementation was associated with a moderate increase in the risk of preterm birth, although further research is required. Vitamin C supplementation may help to prevent women developing pre-eclampsia during their pregnancy, although more research is needed.

This record should be cited as: 
Rumbold A, Crowther CA. Vitamin C supplementation in pregnancy. Cochrane Database of Systematic Reviews 2005, Issue 2. Art. No.: CD004072. DOI: 10.1002/14651858.CD004072.pub2
Assessed as up to date: 
5 September 2004