When the kidney fails the blood cannot be filtered properly. Protein breakdown and water need to be removed by haemodialysis, a mechanical process that passes blood over a special filtering membrane. Natural membranes such as cellulose are used. The more expensive synthetic types are considered more compatible as they cause less of an immune response but it is not clear how real clinical outcomes are affected. The review compared synthetic membranes with cellulose/modified cellulose membranes. Not enough evidence was found to show a beneficial effect for synthetic membranes although some improvements were noted. More research is needed.
Not enough evidence to show the effect of synthetic membranes when compared with cellulose membranes for haemodialysis
8 July 2009
This record should be cited as:
MacLeod AM, Campbell MK, Cody JD, Daly C, Grant A, Khan I, Rabindranath KS, Vale L, Wallace SA. Cellulose, modified cellulose and synthetic membranes in the haemodialysis of patients with end-stage renal disease. Cochrane Database of Systematic Reviews 2005, Issue 3. Art. No.: CD003234. DOI: 10.1002/14651858.CD003234.pub2
Assessed as up to date:
20 May 2005
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