Malignant gliomas are aggressive tumours of the nervous system. Resection (surgery to remove the tumour) may relieve symptoms but there is uncertainty that it extends survival. Biopsy can confirm diagnosis and carries fewer risks, but will not extend survival or improve symptoms. It is controversial as to which procedure is the best management option. One small trial looking at this problem was found but the trial proved inadequate and of low quality to answer the question conclusively. Larger well designed trails are required in the future.
Biopsy versus resection for high grade glioma
16 March 2011
This record should be cited as:
Hart MG, Grant R, Metcalfe SE. Biopsy versus resection for high grade glioma. Cochrane Database of Systematic Reviews 2000, Issue 2. Art. No.: CD002034. DOI: 10.1002/14651858.CD002034
Assessed as up to date:
15 February 2011
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