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Central action beta-blockers versus placebo for neuroleptic-induced acute akathisia

Barnes TRE, Soares-Weiser K, Bacaltchuk J
Published Online: 
12 May 2010

Akathisia is recognised as one of the most common and distressing of the early-onset adverse effects of neuroleptic drugs. This movement disorder is characterised by a subjective report of inner restlessness, mental unease or dysphoria, which can be intense.

This review highlights the limited evidence available to support the use of central action beta-blockers for neuroleptic-induced acute akathisia.