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A single dose of ibuprofen administered orally to treat acute postoperative pain in adults

Derry CJ, Derry S, Moore RA, McQuay HJ
Published Online: 
13 June 2012

Ibuprofen at 200 mg and 400 mg produces a high level of pain relief in about half of those with moderate or severe acute postoperative pain. This is a good result compared with most other analgesics tested in a very well researched model of pain used for demonstrating that drugs can actually produce pain relief. There were no more adverse events than with placebo.