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A single dose of ibuprofen administered orally to treat acute postoperative pain in adults

Derry CJ, Derry S, Moore RA, McQuay HJ
Published Online: 
13 June 2012

Ibuprofen at 200 mg and 400 mg produces a high level of pain relief in about half of those with moderate or severe acute postoperative pain. This is a good result compared with most other analgesics tested in a very well researched model of pain used for demonstrating that drugs can actually produce pain relief. There were no more adverse events than with placebo.

This record should be cited as: 
Derry CJ, Derry S, Moore RA, McQuay HJ. Single dose oral ibuprofen for acute postoperative pain in adults. Cochrane Database of Systematic Reviews 2009, Issue 3. Art. No.: CD001548. DOI: 10.1002/14651858.CD001548.pub2
Assessed as up to date: 
11 May 2009