Cochrane Summaries

Trusted evidence. Informed decisions. Better health.

There is no evidence that aspirin improves the symptoms of vascular dementia

Rands G, Orrell M
Published Online: 
14 November 2012

Low-dose aspirin can improve the prognosis of heart disease and stroke, possibly by reducing clot formation within the blood vessels and helping to maintain or improve blood flow to the heart and brain. Many doctors assume that aspirin will also provide some benefit for people with vascular dementia.

This systematic review shows that there is no evidence to suggest that aspirin is useful for people with vascular dementia. It is possible that vascular dementia and stroke are caused by different pathological processes. Practitioners need to be aware of the risks of aspirin, such as haemorrhages, which can be fatal.


This record should be cited as: 
Rands G, Orrell M. Aspirin for vascular dementia. Cochrane Database of Systematic Reviews 2000, Issue 4. Art. No.: CD001296. DOI: 10.1002/14651858.CD001296
Assessed as up to date: 
4 March 2012