Antioxidant vitamins and mineral supplements to prevent the development of age-related macular degeneration

Age-related macular degeneration (AMD) is a condition affecting the central area of the retina (back of the eye). The retina can deteriorate with age and some people get lesions that can lead to loss of central vision. Some studies have suggested that people who eat a diet rich in antioxidant vitamins (carotenoids, vitamins C and E) or minerals (selenium and zinc) may be less likely to get AMD. The authors identified three large, high quality randomised controlled trials based in Australia, Finland and USA which had investigated the effects of vitamin E and beta-carotene supplementation. This review found no evidence that people in the general population should take antioxidant vitamin or mineral supplements in order to delay the onset of AMD. The results of ongoing trials are awaited.